Publications by authors named "Nienke de Groot"

Swine dysentery, ileitis, and porcine salmonellosis are production-limiting diseases of global importance for swine production. They are caused by infection with , , and serovar Typhimurium, respectively. Currently, the prevention, treatment, and control of these diseases still relies on antimicrobials.

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Purpose: Image guided radiotherapy (IGRT) strategies allow detecting and monitoring anatomical changes during external beam radiotherapy (EBRT). However, assessing the dosimetric impact of anatomical changes is not straightforward. In current IGRT strategies dose volume histograms (DVH) are not available due to lack of contours and dose recalculations on the cone-beam CT (CBCT) scan.

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Background: Immune cell activation and perpetuation of inflammation have been attributed to the neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). Our hypothesis was that the 5-HT system plays a role in GI health and immunity in post-weaning piglets. A disruption of the 5-HT system post-weaning with transcriptional upregulation of 5-HT receptors may be linked to increased cytokine mRNA abundance and immune system activation.

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Article Synopsis
  • Weaning in piglets can trigger inflammation in the intestine, which may hinder their health and increase disease risk, but nutritional strategies like fungal fermented products could help improve their gut health and immune response.
  • In this study, a blend of mannan-rich hydrolyzed copra meal and fermented rye with Agaricus subrufescens was found to significantly reduce certain pro-inflammatory cytokines in the intestines of post-weaning piglets, particularly noticeable by day 15.
  • The results indicated that the feed additive not only modulated immune responses but also affected the structure of the intestines, showing changes in villus height over time and a decrease in the amount of Immunoglobulin A-producing cells, suggesting improved intestinal health.
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Controlling gut inflammation is important in managing gut disorders in the piglet after weaning. Establishing patterns of inflammation markers in the time subsequent to weaning is important for future research to determine whether interventions are effective in controlling gut inflammation. The objective of this study was to evaluate the intestinal inflammatory response during the postweaning period in piglets.

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This study was carried out to evaluate the effect of Selacid Green Growth (GG) or antibiotic growth promoter (AGP) on the performance and economics of grow-finish (GF) pigs. The Selacid GG is a blend of short-chain fatty acids (formic acid, acetic acid, lactic acid, propionic acid, citric acid, and sorbic acid), buffered organic acid (ammonium formate), and a combination of medium-chain fatty acids (C8, C10, and C12). A total of 312 grower pigs (Yorkshire × Landrace × Duroc) with initial body weight (BW) of 26.

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Background: Georgia is a country in the Caucasus region with a traditional backyard and highly variable pig farming system. The practices of such sectors have seldom been described and analyzed to better understand their implication in the introduction and spread of infectious pig diseases. Moreover, the Georgian pig sector was badly hit by an epidemic of African swine fever in 2007 that quickly spread throughout the region.

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