Publications by authors named "Nien-Yi Chang"

Article Synopsis
  • NTRK-rearranged mesenchymal tumors mainly affect soft tissues in kids but can rarely occur in adults too.
  • In a study of 7 adult patients (ages 18-53), researchers looked at tumors in different body parts like the lung, heart, and prostate that had special genetic changes.
  • These tumors had different appearances, some were more serious than others, and while they mostly tested positive for certain proteins, it's important to confirm their diagnosis with more detailed genetic tests.
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Sclerosing pneumocytoma (SP) is a rare benign neoplasm of the lung. Conservative surgical excision is curative with an excellent prognosis. Preoperative diagnosis of SP can be difficult.

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The micropapillary pattern of lung adenocarcinoma was discussed in the 2004 World Health Organization classification and is now proposed as a distinct pattern in the new International Multidisciplinary Classification of Lung Adenocarcinoma Guidelines. The micropapillary pattern is histologically characterized by papillary tufts lacking a central fibrovascular core and is associated with an unfavorable prognosis. Herein, we report the cytological features of lung adenocarcinoma with the micropapillary pattern in a sputum specimen.

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Langerhans cell sarcoma (LCS) is a rare malignancy requiring differential diagnosis from other high-grade nonhematologic and hematologic tumors. The pathogenesis of LCS remains unknown. Notably, LCS and its benign counterpart, Langerhans cell histiocytosis (LCH), are frequently associated with other malignancies.

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