Publications by authors named "Niels Erikstrup Clausen"
Article Synopsis
- Platelet transfusions are commonly administered in ICUs for patients with low platelet counts (thrombocytopenia), but the specific practices and their outcomes are not well-documented.
- In a study of 504 ICU patients across Europe and the U.S., 20.8% received platelet transfusions, primarily using pooled products, with varying practices in dosage and volume across different countries.
- The research found that while platelet transfusions are frequent, they provide limited increases in platelet counts, indicating potential inconsistencies in their effectiveness and administration practices.
Article Synopsis
- Thrombocytopenia, defined as a low platelet count, is a frequent issue in ICU patients and is linked to poorer health outcomes, including higher mortality rates.
- A study involving 1166 ICU patients across 52 ICUs in 10 countries found that 43.2% had thrombocytopenia, with nearly one-quarter presenting with it upon admission.
- Thrombocytopenia at ICU admission was statistically associated with increased 90-day mortality, and while 22.6% of those affected received platelet transfusions, the majority were given as a precautionary measure.
Introduction: During the first wave of the COVID-19 pandemic, visits to hospitals were prohibited. Therefore, new ways of communicating with relatives about and with patients were needed. This study aimed to explore experiences made with video calls in an adult ICU.
View Article and Find Full Text PDFThe effect of prostacyclin (Iloprost) infusion at a dose of 1 ng/kg/min for 72 hours compared to placebo in mechanically ventilated patients with COVID-19: A structured summary of a study protocol for a randomized controlled trial.
Trials
August 2020
Objectives: To investigate the effect of continuous infusion of the potential endothelial cytoprotective agent prostacyclin (Iloprost) 1 ng/kg/min vs. placebo for 72 hours on pulmonary endotheliopathy in mechanically ventilated COVID-19 patients.
Trial Design: A multicenter, randomized (1:1, active: placebo), blinded, parallel group exploratory trial PARTICIPANTS: Inclusion criteria are: Adult patients (>18 years); Confirmed COVID-19 infection; Need for mechanical interventions; Endothelial biomarker soluble thrombomodulin >4ng/ml.
Background: Automated external defibrillators (AEDs) have proven effective when used by GPs. Despite this and the latest guidelines from the European Resuscitation Council, there are no recommendations for Danish GPs regarding proper equipment to treat cardiac arrest. Currently, there are no published data on the distribution of AEDs among GPs in Denmark.
View Article and Find Full Text PDFPancreatic pseudocyst, a common complication of acute or chronic pancreatitis, can be an important differential diagnosis to aorta aneurism. A 46-year-old man under investigation for lung cancer presented with chest pain, dysphagia and dyspnoea. A chest X-ray showed opacity in the mediastinum opposite aorta.
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