Candidate Biomarkers for the Diagnosis of Transient Ischemic Attack: A Systematic Review.

Background And Purpose: A rapid serum biomarker that confirms or rules out a transient ischemic attack (TIA) would be of great value in clinical practice. We aimed to systematically review current evidence for the diagnostic accuracy of blood biomarkers in the early diagnosis of TIA.

Methods: This is a systematic review with quality appraisal of individual studies using the QUADAS-2 tool.

Patient delay in TIA: a systematic review.

Background: Patients who suffer a transient ischemic attack (TIA) have a high short-term risk of developing ischemic stroke, notably within the first 48 h. Timely diagnosis and urgent preventive treatment substantially reduce this risk. We conducted a systemic review to quantify patient delay in patients with (suspected) TIA, and assess determinants related to such delay.