Impact of Pneumococcal Vaccination on Nasopharyngeal Carriage of and Microbiota Profiles in Preschool Children in South East Poland.

In 2017, Poland introduced the 10-valent pneumococcal conjugate vaccine (PCV) into its national immunization schedule. This prospective study was conducted between March and June 2020 to determine the impact of vaccination on prevalence of the nasopharyngeal carriage of in 176 healthy children and to determine how conjugate vaccines indirectly affect colonization of nasopharyngeal microbiota. Pneumococcal isolates were analyzed by serotyping and antimicrobial resistance tests.

Bacterial aetiology of chronic otitis media with effusion in children - risk factors.

Background: Otitis media with effusion (OME) may occur spontaneously because of poor Eustachian tube function or as an inflammatory response following AOM. Bacterial involvement in OME has been widely reported, with various available methods to identify pathogens from middle ear effusion, including traditional culture methods and polymerase chain reaction (PCR).

Objectives: The primary goal of this study was to evaluate the bacteriological profile of middle ear effusion in OME.

Resistant Streptococcus pneumoniae strains in children with acute otitis media- high risk of persistent colonization after treatment.

Background: Despite advances in the development of pneumococcal conjugate vaccines, acute otitis media (AOM) is a common childhood infection, caused mainly by Streptococcus pneumoniae. It has been suggested that persistence of pneumococcal nasopharyngeal carriage is a risk factor for subsequent recurrent infections.

Methods: In this study we evaluate the relationship between 55 pneumococcal strains obtained from nasopharynx/oropharynx (NP/OP) and middle ear fluid (MEF) of 62 children, aged between 1 and 16 years, during AOM (including recurrent/treatment failure AOM, and post-treatment visits), based on their phenotypic and genotypic characteristics performed by analyses of serotype, antibiotic susceptibility patterns and multilocus sequence typing.

First report of a isolated from middle ear fluid of an infant with recurrent acute otitis media.

was originally isolated from goat milk. This uncommon coagulase-negative staphylococcus, usually associated with animals, has only infrequently been detected in human clinical specimens. Its association with acute otitis media has not been demonstrated so far.

Serotypes and antibiotic resistance of Streptococcus pneumoniae from adenoids in preschool children with recurrent upper respiratory tract infections.

We investigated children aged 2-5, who had gone adenoidectomy for recurrent and/or persistent symptoms of upper respiratory tract infections for prevalence of pneumococci in adenoid tissue. Serotypes and antibiotic resistance patterns of the isolated pneumococci were determined and also risk factors of pneumococcal colonization were defined. S.

Risk factors for otolaryngological foreign bodies in Eastern Poland.

Objective: To identify the sociodemographic characteristics and risk factors associated with suspected foreign bodies in the ear, nose, throat, airway, and esophagus among Polish children.

Study Design: Case series with chart review. Setting Tertiary care medical center.

Esophageal foreign bodies in pediatric patients: a thirteen-year retrospective study.

We discuss clinical symptoms and radiological findings of variable esophageal foreign bodies as well as therapeutic procedures in Caucasian pediatric patients. A retrospective study of 192 cases of suspected esophageal foreign bodies between 1998 and 2010 was conducted. Data were statistically analyzed by chi-square test.

Dendritic cells and lymphocyte subpopulations of the adenoid in the pathogenesis of otitis media with effusion.

Objective: To assess dendritic cells and lymphocyte subpopulations of adenoid and peripheral blood in patients with adenoid hypertrophy and otitis media with effusion (OME). To explain the influence of immunological status of adenoid on the development of OME.

Methods: The examined group covered 123 surgically treated patients due to adenoid hypertrophy (39 children with coexisting OME).

The phenotypic and genetic biofilm formation characteristics of coagulase-negative staphylococci isolates in children with otitis media.

Objective: Medical biofilms are involved in a number of chronic infections including otitis media with effusion and chronic rhinosinusitis, which are common pediatric infectious diseases. The purpose of the study was to analyze the phenotypic and genotypic indicators of biofilm formation of coagulase negative staphylococci isolates in children with otitis media with effusion, and in children with chronic rhinosinusitis as a comparison group by using three different detection methods.

Methods: Forty nine children aged from 2 to 6 years old, diagnosed with otitis media with effusion were enrolled to the study.

Voice after radiotherapy of the larynx carcinoma.

Background: The study presents the evaluation of the phonatory function of the larynx after radiotherapy. The research covered the patients from the rural areas of Poland who revealed neoplastic changes in the glottis area.

Material And Methods: The test group consisted of 45 men aged 41-78 years with the carcinoma of the larynx with T1 and T2 progression types of cancer, according to the TNM classification.

[Choanal atresia an institutional review].

Unlabelled: Choanal atresia is a rare congenital disease, it occurs in 1/8000 live newborns.

Aim Of The Study: retrospective review of patients with choanal atresia treated at the Department of Pediatric Otolaryngology of Medical University in Lublin. Twenty-two children were evaluated, 16 females, 6 males, age range from 6th day to 11th year of life, operated between 2004 and 2009.

[Sinusitis--judicious antibiotic treatment].

The paper presents different forms of sinusitis in children and adults as well as the patomechanism of sinusitis of infective and non-infective origin. The role of bacterial infection has been discussed. Participation of major pathogens of URTI such as S.

Assessment of pulmonary function and nasal flow in children with adenoid hypertrophy.

Objective: Adenotonsillar hypertrophy is the most common cause of upper airways obstruction in children. The consequences of this disorder were analyzed by many researchers. The aim of the study was the assessment of pulmonary function and nasal flow in children with adenoid hypertrophy.

Nasal ganglioglioma--difficulties in radiological imaging.

Ganglioglioma is a tumour containing both astrocytic and neuronal components. Most gangliogliomas are observed in the brain, but may also manifest as a nasal glioma. Approximately 250 cases of nasal gliomas have been described in the literature.

[Current opinions on pathogenesis and treatment of otitis media with effusion in children].

Otitis media with effusion (OME) is one of the most often diagnosed diseases in the pre-school children. OME is defined as the presence of effusion behind the intact tympanic memebrane without symptoms of acute infection. Pathogenesis of OME is multifactorial and represents the interactions between environmental, social, anatomical and infectious factors and an allergy.

Cervical lymphadenopathy in children--incidence and diagnostic management.

Objective: Palpable lymph nodes are common due to the reactive hyperplasia of lymphatic tissue mainly connected with local inflammatory process. Differential diagnosis of persistent nodular change on the neck is different in children, due to higher incidence of congenital abnormalities and infectious diseases and relative rarity of malignancies in that age group. The aim of our study was to analyse the most common causes of childhood cervical lymphadenopathy and determine of management guidelines on the basis of clinical examination and ultrasonographic evaluation.

[Simultaneous detection of three histopathologically different kinds of cancer].

Introduction: The problem of primary mixed neoplasms has been recently a subject of numerous works trying to find out their pathogenic mechanisms, early detection, clinical course and treatment opportunities.

Material And Methods: The rare case of detection of the three histopathologically different kinds of cancer in the three diffewent places for a 71-year-old man, who did not report any disorders, has been described.

Results: After histopathological examination carcinoma flat epithelium of the nose, carcinoma basal cell of the left cheek and adenocarcinoma aciniform partially solid of the right lung were diagnosed.

[Evaluation of osteomeatal complex in children with chronic sinusitis].

The aim of this publication was estimation of osteomeatal complex and its visualisation by means of CT in children having been treated conservatively and surgically because of sinusitis. There were analyzed 47 children age 4 to 18 years who had been treated in Dept. of Children Otolaryngology, Phoniatry and Audiology of Medical University in Lublin during 2001-2005.

Evaluation of the association between atypical bacteria infections and respiratory tract diseases with emphasis on bronchial asthma exacerbations in children.

Mycoplasma pneumoniae and Chlamydia pneumonie are important etiological agents responsible for human respiratory tract diseases. Recently, these atypical microorganisms received much attention regarding their role in bronchial asthma pathogenesis, which is one of the most frequent chronic diseases in children. The aim of the study was to investigate the association between infections caused by these pathogens and respiratory tract diseases in children.

Acoustic estimation of voice when incorrect resonance function of the nose takes place.

Phonation is a sensitive indicator of palatopharyngeal obstruction and its physiological force. The aim of the study was to evaluate the influence of nasality on the voice quality. The study was carried out on 125 patients divided into three subgroups.

The application of ultrasound contrast, 3D imaging and tissue harmonic imaging in the differential diagnosis of lymph nodes enlargement in children.

The application of Power Doppler mode examination introduced the assessment of vascularisation and measurement of blood flow parameters in lymph node's vessels as a differentiating criterion of benign and malignant lymphadenopathy. However, those criteria appeared insufficient in evaluation of the malignancy grade of enlarged lymph nodes, especially in the cases of lymph nodes with invisible or scantly visible vascularisation in Power Doppler mode. Introducing contrast media in ultrasonographic examinations enabling intensification of the Doppler signal even by 20 dB creates the hope of increasing diagnostic efficacy of ultrasonography in evaluation of vascularisation in lymph nodes enlargement.

TEOAE after treatment of otitis media with effusion.

Otoacoustic emission is a noninvasive method of testing inner ear function. OAE is susceptible to the influence of many different factors of which the principal ones are the changes taking place in the middle ear. In transiently evoked otoacoustic emission (TEOAE) we deal with double signal transmission through the middle ear.

Personality features of children treated due to vocal nodules.

There were estimated 14 features of personality of the children treated for vocal nodules. The purpose of study was definition of the selected features, which are typical of the examined group. The conclusion drawn from the conducted studies was: the children cured of the vocal nodules are more excitable, nervous, independent and often--individualists.

[Multicenter, open clinical investigation on using cefprozil in therapy of otitis media in children].

We present results of multi center, open clinical trial on using cefprozil (cephalosporin II generation) in acute otitis media in children. Results indicate very good treatments effect (89.3%) and good tolerance of the drug (10.