[Tumor-induced medullary compression--experiences with 570 patients].

On the basis of patients treated at the Clinic for Neurosurgery in Leipzig in the period from 1952 to 1986 with a total of 570 suffering from spinal tumours, the nature of non-traumatic medullary compression is discussed, taking into consideration the relative frequency of the individual kinds of tumours as well as the distribution and the level of the location. The clinical aspects of medullary compression is elaborated, the differential-diagnostic of the demarkation possibilities between intra- and extramedullary tumour sites are discussed. In a retrospective consideration it must be stated that only 25 per cent of all patients with spinal tumours are operated on in an early stage (I and II) and only 60 per cent in the stage of incomplete transverse lesion of the with paraplegia (III).

[Electroencephalographic findings in tumors of ventricles I-III].

The EEG findings in 177 patients with mainly malignant tumours in the region of the ventricles I-III have been evaluated. The changes were dependent upon the size of the tumours and the kind and direction of their infiltration growth into the paraventricular structure. In case of purely intraventricular spreading of the disturbance of the cerebral fluid circulation normal curves were found.

[Neuro-ophthalmologic findings in tumors of ventricles I-III].

The ophthalmological findings obtained in 254 patients with space occupying processes of the lateral and third ventricles are analysed. Visual disturbances (78%), defects of the visual field (69%), findings of the fundus of the eye (67%) and motility restrictions (24%) were identified. Only in eight per cent the findings of the eye-ground no particular findings were observed.

[Neuroradiologic findings in tumors of ventricles I-III].

In the period from 1953-1983, apart from the computer tomography the following neurodiagnostic methods were employed for the diagnosis of ventricular tumours: native radiography of the skull, PEG, ventriculography, positive ventriculography, angiography and cerebral scintigraphy. This study shows that a clear change in the importance of the various methods has taken place in the above mentioned period of time. The X-ray pictures of the skull taken without a contrast medium have become less important in the last few years although they showed direct and indirect signs of the tumours in almost all ventricular tumours.

[Operative treatment of tumors of ventricles I-III following experiences 1953-1983].

A report is given on the experience gained in 254 patients presenting processes of the ventricles I-III at the Leipzig Hospital within a period of thirty years. The rate of radical operations rose from 29% to 60%. At present, however, inoperability is restricted almost exclusively to general surgical aspects.

[Processes of ventricles I-III. Review of the patient population of the Neurosurgery Clinic of the Karl Marx University 1953-1983].

Within three decades 254 patients with processes of the brain ventricles I-III have been treated at the Leipzig Neurosurgical Clinic. The article subdivides the patients in general and according to the histology, localisation, lateral differences, dignity, operability as well as the postoperative lethality. The evaluation gives many clues with respect to the diagnostics and therapy of these ventricular processes.

[Clinical aspects of intracranial epidermoids and dermoids].

The authors discuss 21 epidermoids and 6 dermoids of the craniocerebral region, which occurred in patients of the Leipzig Neurosurgical Clinic within a period of ten years. Main localisation was the sellar region. The clinical symptoms (frequently with lacking signs of brain pressure), the diagnosis and prognosis of the malformation tumours are dealt with.

[Tumors of the 4th ventricle and the craniospinal transitional zone. Review of patients of the Neurosurgical Clinic of the Department of Medicine of the Karl Marx University].

From a total of 1,028 infratentorial tumours operated on at the Neurosurgical Hospital of the Section Medicine of the Karl-Marx University Leipzig in the last 30 years, 167 tumours in the region of the 4th ventrical have been selected. Their statistical processing was carried out with respect to specific localisation, average age, kind of tumour, sex, clinical findings, duration of case history, application of instrumental diagnostic procedures and radicality of operation, success and failure. Some fundamental conclussions are drawn.

[Angioarchitecture of gliomas. 1: Models of cerebral vessels, casting materials, preparation methods, changes in tumor vessels].

A report is given on the study of cerebrovascular systems in experimental animals and corpses and the demonstration of cerebral tumours be means of models of vascular system. After a survey of the development of model representation, the technique of the vessel injection, the various injection materials and methods of preparation are described in detail. Advantages and disadvantages of the individual methods and certain peculiarities in model representations of transplantation tumours and various human brain tumours are presented.

[Filling of the Circle of Willis in carotid angiography using halothane anesthesia].

A comparative study of 150 carotid angiographies carried out under local anaesthesia and the same number under halothane anaesthesia did not show any great deviation from the well-known filling rates of the counter-lateral carotid region and the ipsilateral A. cerebri posterior nor any striking differences in the two methods of anaesthesia which could convince of a favourable influence of halothane on the demonstration of the vessels. The causative factors of the filling of adjacent vascularisation regions can certainly only be explained from the complex co-action of physiological and any external factors in cerebral angiography.

[The influence on water-electrolyte balance through osmotherapy for decreasing intracranial pressure].

On the basis of a group of neurosurgical patients showing a differing composition, various procedures of the dehydrating therapy in the pre- and postoperative phases for decreasing the increased intracranial pressure were studied. In addition to the continuous recording of the intracranial pressure, the electrolyte and water balance was measured by recording the plasma, urinary, and cerebrospinal-fluid electrolytes and their osmolarities and the urinary output was determined. Besides, specific measurements of the haematocrit, of the central venous pressure and the arterial mean pressure brought pathophysiological findings on the dehydration.

[400 intraspinal space-narrowing processes--a clinical study].

Among 400 observations by the authors, 2 per cent were admitted without and another 22 per cent with slight neurological disturbances. An incomplete transverse lesion of the cord with paraplegia was found in 61.7 per cent, a complete paralysis in 14.

[Reperfusion following cerebrovascular arrest].

An account is given of a case of artificial perfusion of isolated organ after operative correction of an angiographically recorded standstill of the circulatory system. Criteria of cerebral death and determination of the time of death are discussed.