Patterns of Mental Health and Resilience among Nurses and Physicians throughout the COVID-19 Pandemic: A Three-Year Longitudinal Study.

Objective: The COVID-19 pandemic is associated with increased difficulties in emotional wellbeing among healthcare workers. The current investigation assesses how changes in depression and anxiety symptoms fluctuate relative to resilience across three time points: baseline, one-year, and two-year follow up among a cohort of physicians and nurses (N = 728).

Methods: Generalized linear mixed modeling for repeated measures was used to assess the association between resilience and mental health symptoms using validated measures for all variables.

Physician challenges and supports during the first wave of the COVID-19 pandemic: A mixed methods study.

Introduction: During the COVID-19 pandemic, physicians encountered significant COVID-19-related negative experiences and psychological distress in both their personal and professional lives. To understand the factors that negatively impact physician well-being, a number of studies have pointed to multiple work system factors such as excessive workload and workflow interruptions. In addition, studies have shown that positive interpersonal relationships that provide social support may also serve as a buffering role against psychological distress.

Evidence for validity of the epidemic-pandemic impacts inventory (brief healthcare module): Internal structure and association with other variables.

The COVID-19 pandemic has subjected healthcare workers to enormous stress. Measuring the impact of this public health emergency is essential to developing strategies that can effectively promote resilience and wellness. The Epidemic-Pandemic Impacts Inventory Supplemental Healthcare Module-Brief Version (EPII-SHMb) was developed to measure impacts among occupational cohorts serving on the front lines of healthcare.

The Impact of Physicians' COVID-19 Pandemic Occupational Experiences on Mental Health.

Objective: To examine the association between a number of negative COVID-19 occupational experiences and probable anxiety, depression, and PTSD among physicians.

Methods: Cross-sectional examination of longitudinal registry data consisting of physician personal and occupational well-being. Multivariable logistic regressions were performed to determine the association between negative COVID-19 experiences and outcomes.

Prevalence of molecular subtypes of invasive breast cancer: A retrospective study.

Background: Classification of breast cancers into different molecular subtypes using immunohistochemistry as a surrogate tool to DNA microarray technology has been identified. Aim of this study was to find the precise prevalence of molecular subtypes of invasive breast carcinoma using immunohistochemistry and to correlate it with histological and clinical prognostic factors.

Methods: A descriptive study design wherein 56 breast carcinoma cases diagnosed between May 2012 and Apr 2014 were reviewed and molecular subtyped using relevant immunohistochemical markers.

Altered activation in fronto-striatal circuits during sequential processing of conflict in unmedicated adults with obsessive-compulsive disorder.

Background: The aim of this study was to examine the functioning of fronto-striatal brain circuits that support self-regulatory capacities including conflict resolution and sequential processing in unmedicated adults with obsessive-compulsive disorder (OCD).

Methods: We compared functional magnetic resonance imaging blood oxygen level-dependent response in 22 adults with OCD with 22 healthy, age-matched control subjects during performance of a Simon Spatial Incompatibility task. We used general linear modeling to compare groups in their patterns of brain activation during correct responses to conflict-laden stimuli and explore the effects of trial sequence on group differences.