Low-Cost Histopathological Mitosis Detection for Microscope-acquired Images.

Cancer outcomes are poor in resource-limited countries owing to high costs and insufficient pathologist-population ratio. The advent of digital pathology has assisted in improving cancer outcomes, however, Whole Slide Image scanners are expensive and not affordable in low-income countries. Microscope-acquired images on the other hand are cheap to collect and can be more viable for automation of cancer detection.

Compound Homozygous Rare Mutations in PLCE1 and HPS1 Genes Associated with Autosomal Recessive Retinitis Pigmentosa in Pakistani Families.

Background: Retinitis pigmentosa (RP) belongs to pigmentary retinopathies, a generic name for all retinal dystrophies with a major phenotypical and genotypical variation, characterized by progressive reduction of photo-receptor functionality of the rod and cone. Global prevalence of RP is ~ 1/4000 and it can be inherited as autosomal dominant (adRP), autosomal recessive (arRP) or X- linked (xlRP). We designed this study to identify causative mutations in Pakistani families affected with arRP.

Metastatic Choriocarcinoma of the Breast: A Rare Entity.

Breast neoplasms are becoming more common in the last few years. Among these masses, metastasis to the breast is rare. Extra-gestational choriocarcinoma is extremely rare among breast neoplasms.