[Polymorphisms of the SCN10A Gene in Patients With Sick Sinus Syndrome].

Purpose: To study association of rs6795970 polymorphism of SCN10A gene with development of idiopathic sick sinus syndrome (ISSS).

Materials And Methods: We examined 109 patients with ISSS, 59 their healthy 1‑st-, 2‑nd-, and 3‑rd-degree relatives, and 630 controls. Patients with ISSS were divided into subgroups according to gender and clinical variant of the disease.

[The Role of the I/D Polymorphism of the ACE Gene in the Development of Atrial Fibrillation].

Objective: To study associations of I / D polymorphism of the ACE gene with risk of atrial fibrillation (AF) with the aim of detecting groups of patients prone to development of this disease.

Materials And Methods: We examined 90 probands with confirmed diagnosis of AF and 144 their I, II, III degrees relatives. These families constituted a core group of our study.