Publications by authors named "Nicolo V"

Background/objectives: Mental health disorders pose a substantial challenge for healthcare workers, particularly in the post-COVID-19 era. Public health medical residents (PHRs) played a pivotal role during the pandemic and were significantly affected by the heavy workload. This study aims to uncover potential associations between workload characteristics and symptoms of anxiety and insomnia in Italian PHRs based on data collected in 2022 through the Public Health Residents' Anonymous Survey in Italy (PHRASI) study.

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Article Synopsis
  • Unhealthy behaviors (UBs) like alcohol abuse, lack of exercise, and sleep problems can significantly impact mental health, particularly concerning depression and anxiety among medical residents.
  • The study utilized a nationwide survey in Italy, incorporating an 88-item questionnaire and validated tools to assess UBs and mental health outcomes among 375 participants.
  • Three distinct clusters emerged from the data, with CL1 showing high levels of alcohol abuse and insomnia linked to severe depressive and anxiety symptoms, highlighting the need for targeted mental health interventions in public health education.
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Medical residents constitute a vulnerable population susceptible to mental health disorders. In Italy, this was evident during the COVID-19 pandemic, when medical residents served on the front line and provided significant support to healthcare services. Therefore, the working group on "Public Mental Health" of the Medical Residents' Council of the Italian Society of Hygiene, Preventive Medicine, and Public Health (S.

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Background: Mental well-being should be prioritized in public health as it represents a valuable resource for individuals and communities, influencing behavior, social cohesion and social inclusion. The support individuals receive from their social networks can have a significant impact on mental well-being. This study used data from the Public Health Residents' Anonymous Survey in Italy, a nationwide cross-sectional survey.

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Objective: The purpose of this study is to validate the 13-item version of the Work-Related Stress Questionnaire (WRSQ) on a representative sample of Italian public health residents.

Materials And Methods: The WRSQ was administered as part of the Public Health Residents' Anonymous Survey in Italy (PHRASI) from 14 June to 26 July 2022. Collinearity between each questionnaire item was assessed with Kendall's τ statistic.

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Despite the high impact of the COVID-19 pandemic on social interactions and healthcare workers' (HWs') mental health, few studies have investigated the association between social network characteristics and HWs' mental health, particularly during the pandemic. Therefore, we aimed to assess the associations between public health residents' (PHRs') social network characteristics and depression. We used data from the Public Health Residents' Anonymous Survey in Italy (PHRASI), a nationwide cross-sectional study.

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Depression is a widespread condition, which increased during the COVID-19 pandemic among healthcare workers as well. The large workload of the pandemic response also affected Public Health Residents (PHRs) who played an important role in infection prevention and control activities. This work aims to assess depression in Italian PHRs, based on data collected through the PHRASI (Public Health Residents' Anonymous Survey in Italy) study.

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The COVID-19 pandemic has evolved into a severe psychosocial crisis affecting patients, their relatives, friends, and healthcare professionals. In Italy, public health residents (PHRs) remain essential to the national response to the pandemic. To assess their mental sphere, the "Public Mental Health" working group of the medical residents' Assembly of the Italian Society of Hygiene and Preventive Medicine has designed the Public Health Residents' Anonymous Survey in Italy (PHRASI).

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Article Synopsis
  • - Spinocerebellar ataxia 28 (SCA28) is a genetic neurodegenerative disorder linked to mutations in the AFG3L2 gene, impacting mitochondrial function, but its mechanisms and treatments remain poorly understood.
  • - A new knock-in mouse model expressing a specific patient-derived mutation (p.Met665Arg) demonstrated developmental normality but exhibited signs of cerebellar ataxia and altered electrophysiological activity in Purkinje cells.
  • - Investigations revealed mitochondrial dysfunction in mutant mice, including reduced energy production and altered morphology, suggesting that these mitochondrial changes might be crucial for understanding SCA28 and developing potential therapies.
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Neuregulin 1 (NRG1) is a growth factor produced by both peripheral nerves and skeletal muscle. In muscle, it regulates neuromuscular junction gene expression, acetylcholine receptor number, muscle homeostasis and satellite cell survival. NRG1 signalling is mediated by the tyrosine kinase receptors ErbB3 and ErbB4 and their co-receptors ErbB1 and ErbB2.

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In seeking to ease the rehabilitation of refugees there has generally been a failure to take account of the complexity of the refugees' experience of suffering and loss. In this their psychological and emotional well-being as well as the social and economic aspects of the question have frequently been of only peripheral concern, and the response to the psychological impact of violence has been primarily focused on the concept of Post-Traumatic Stress Disorder (PTSD). This approach assumes a pathological response to stress that is both universal across different cultures and centred on the potential of pathologizing coping strategies that might be essential not only for survival but also for psychological well-being.

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