as a Model for the Study of Fungal Pathogens: Advantages and Disadvantages.

The study of pathogenicity and virulence of fungal strains, in vivo in the preclinical phase, is carried out through the use of animal models belonging to various classes of mammals (rodents, leproids, etc.). Although animals are functionally more similar to humans, these studies have some limitations in terms of ethics (animal suffering), user-friendliness, cost-effectiveness, timing (physiological response time) and logistics (need for adequately equipped laboratories).

Identification of Virulence Factors in Isolates of , and with Low Susceptibility and Resistance to Fluconazole and Amphotericin B.

Emerging life-threatening multidrug-resistant (MDR) species such as the species complex, (sin. ), and other species are considered as an increasing risk for human health in the near future. (1) Background: Many studies have emphasized that the increase in drug resistance can be associated with several virulence factors in and its knowledge is also essential in developing new antifungal strategies.