Different Temperature and UV Patterns Modulate Berry Maturation and Volatile Compounds Accumulation in sp.

Volatile compounds (VCs) in grapevine berries play an important role in wine quality; however, such compounds and vine development can be sensitive to environmental conditions. Due to this sensitivity, changes in temperature patterns due to global warming are likely to further impact grape production and berry composition. The aim of this study was to determine the possible effects of different growing-degree day accumulation patterns on berry ripening and composition at harvest.

Chronic dry eye induced corneal hypersensitivity, neuroinflammatory responses, and synaptic plasticity in the mouse trigeminal brainstem.

Background: Dry eye disease (DED) is a multifactorial disease associated with ocular surface inflammation, pain, and nerve abnormalities. We studied the peripheral and central neuroinflammatory responses that occur during persistent DED using molecular, cellular, behavioral, and electrophysiological approaches.

Methods: A mouse model of DED was obtained by unilateral excision of the extraorbital lachrymal gland (ELG) and Harderian gland (HG) of adult female C57BL/6 mice.

Pomace limits tannin retention in Frontenac wines.

The impact of different factors (must protein treatment: bentonite and heat; pomace: fermented with and without; tannin addition: 0-9 g/L; and time of maceration: 0-11 days) on tannin, pigment, and protein extraction/retention in Frontenac wines was investigated. Wine tannin concentration and composition were determined by HPLC-fluorescence. Protein and pigment parameters were analysed by BCA assay and Boulton's method, respectively, using UV-spectrophotometry.

Proinflammatory Markers, Chemokines, and Enkephalin in Patients Suffering from Dry Eye Disease.

Dry eye symptoms are among the leading complaints in ophthalmology. Dry eye disease (DED) is associated with significant pain affecting quality of life. Cellular and molecular mechanisms underlying ocular pain associated with DED are not fully understood.

Co-fermentation of red grapes and white pomace: A natural and economical process to modulate hybrid wine composition.

The impact of co-fermenting white grape pomace (WP) and red grape pomace (RP) on the composition of interspecific hybrid wine was studied using the Vitis sp. 'Frontenac' and 'Vidal'. The proanthocyanidin and anthocyanin content of the resulting wines were analysed by HPLC-fluorescence and UPLC-MS/MS, respectively.

High-dose ketoconazole therapy in prostatic cancer. A pilot study.

There may be contraindications to oestrogen therapy for prostatic carcinoma, and also patient objections to orchidectomy as a form of therapy. Ketoconazole, a systemic antifungal drug, was evaluated in a dosage of 200 mg 8-hourly given orally as an alternative method of lowering serum testosterone levels. Nineteen patients were studied; 1 was withdrawn because of nausea and vomiting.

[New results on the phage typing of Yersinia enterocolitica, concerning more of 4 000 strains of various origins (author's transl)].

1) The phage typing of Y. enterocolitica has been made on more than 4,000 strains of various origins by means of 2 sets of phages. The 1st one, composed of 12 phages extracted from lysogenic strains of the same species has permitted to distinguish 10 phages types numbered from I to VIII and from IXa to IXb among the 3,323 lysotypable strains on the 4,366 examinated.