The study aimed to compare the salivary cortisol response after exercise in children with asthma versus healthy children, focusing on the clinical relevance of lower basal cortisol levels in children with asthma.
Nineteen prepubertal children with asthma and twenty healthy counterparts underwent a standardized 20-m shuttle-run test, measuring salivary cortisol levels before, immediately after, and 15 minutes after exercise.
Results showed that a significantly lower percentage of asthmatic children (35.0%) exhibited an increase in salivary cortisol levels compared to healthy children (84.2%), indicating that asthmatic children on inhaled corticosteroids have a diminished cortisol response to exercise.
The study aimed to assess if standardized exercise tests can effectively evaluate adrenal response by measuring salivary cortisol levels in healthy prepubertal children.
During exercise tests (cycling and a running shuttle), cortisol levels showed no change or decrease immediately after, but increased significantly after the shuttle-run test at 15 minutes, indicating different responses based on the type of exercise.
The findings suggest that the shuttle-run test could be a practical, non-invasive way to evaluate adrenal response in healthy prepubertal children, as opposed to cycling tests which did not show the same increase in cortisol.