Histopathological changes of renal tissue following sodium fluoride administration in two consecutive generations of mice. Correlation with the urinary elimination of fluoride.

The present study was designed to investigate the toxic effects (evaluated as histopathological changes) of sodium fluoride on the kidney in two consecutive generations of NMRI mice. An attempt to correlate the toxicity with the urinary elimination of fluoride has been made, as urinary fluoride excretion has been widely used as an indicator of fluoride intake and exposure. Six mixed (males and females) animal groups have been constituted by dividing the populations of mice derived from pregnant females (named "mothers" 0.

Testicular histopathological changes following sodium fluoride administration in mice.

It has been revealed that excessive fluoride intake on long-term is associated with toxic effects and can damage a variety of organs and tissues in the human body, including the male reproductive system. However, the molecular mechanisms of fluoride-induced male reproductive toxicity are not well understood. The study wants to get news concerning the effects of natrium fluoride on testicular tissues when this substance is administrated to a population of mice.

Alveolar bone dehiscences and fenestrations: an anatomical study and review.

Aim: To determine the prevalence and distribution of fenestrations and dehiscences of the jaw bones among the Caucasian population, to find if any correlations can be established between their occurrence and certain teeth characteristics and to discuss the clinical implications the defects of alveolar process could have.

Material And Methods: 138 skulls of specimens ranging from 21 to 54 years of age, having either complete dentition or reduced number of missing teeth were studied. Teeth found to have one of the two defects were examined for signs of faceting (attrition) that was considered an indicative for excessive occlusal forces and were submitted (except for the case of the third molars) to an analysis concerning their bucco-lingual inclination in the jaw.