Publications by authors named "Nicole Vodrazkova"
Article Synopsis
- Human biomonitoring (HBM) data in Europe is often fragmented, but assessments were made for exposure levels in children and adult women from 2000 to 2021 using harmonized methods and biobanked samples.
- Analysis showed decreasing trends in harmful phthalate metabolites and BPA among children and women, respectively, alongside increasing levels of substitutes like DINCH, BPF, and BPS.
- While clear causal relationships weren't established, the findings indicate the effectiveness of EU chemical regulations, showing reduced exposure to restricted substances but a rise in their substitutes.
Background: Perfluoralkylated substances (PFASs) are persistent and bioaccumulative environmental contaminants. They are included on the list of emergent compounds monitored in the frame of HBM4EU project.
Objectives: To analyze PFASs levels in human milk samples collected in the period 2006 through 2017, to follow their time trends, to assess the PFASs exposure in breastfed infants, to calculate the daily intake of PFASs and to compare it with the tolerable daily/weekly) intakes and to quantify risk from exposure using the hazard quotient and hazard index approach.