Memory outcome after temporal lobe epilepsy surgery: corticoamygdalohippocampectomy versus selective amygdalohippocampectomy.

Object: The aim of this study was to compare IQ and memory outcomes at the 1-year follow-up in patients with medically refractory mesial temporal lobe epilepsy (MTLE) due to hippocampal sclerosis. All patients were treated using a corticoamygdalohippocampectomy (CAH) or a selective amygdalohippocampectomy (SelAH).

Methods: The data of 256 patients who underwent surgery for MTLE were retrospectively evaluated.

Atypical speech activations: PET results of 92 patients with left-hemispheric epilepsy.

Purpose: Language lateralization and factors that may influence language lateralization were investigated using positron emission tomography.

Methods: Ninety-two right-handed patients who had left-sided lesions (tumors, focal cortical dysplasia, and vascular lesions) and 19 right-handed normal subjects were included and synonym generation task was used for evaluation of language lateralization.

Results: As expected, the majority of individuals in both groups showed left hemisphere dominance.

Functional results of electrical cortical stimulation of the lower sensory strip.

The aim of this paper is to provide functional results obtained from electrical cortical stimulation of the lower postcentral gyrus in patients who underwent either lesional or non-lesional epilepsy surgery. Group I (n=393) included those patients with gliosis or normal tissue and Group II (n=107) included patients with space-occupying lesions. For cortical stimulation, a unipolar voltage-controlled electrode was used.

Superficial anastomotic veins: neurosurgical view depending on 251 craniotomies.

Background: Superficial anastomotic veins (SAVs) have been studied extensively but little attention has been paid to clinical studies. The aim of this study is to provide variations in the drainage patterns of SAVs depending on the intraoperative findings.

Methods: A total of 251 craniotomies due to intractable temporal lobe epilepsy were performed between 1972 and 1987 at the Montreal Neurological Institute.

Atypical language lateralization in patients with left hippocampal sclerosis: does the hippocampus affect language lateralization?

Aim: To provide information related to atypical language activations (right or bilateral) in positron emission tomography in patients with left clear-cut hippocampal sclerosis.

Material And Methods: Twelve right-handed patients who had been operated on left-sided hippocampal sclerosis and 12 right-handed normal subjects were included and the synonym generation task was used for evaluation of language lateralization.

Results: Atypical language activations were frequently found in the patients compared to the controls.

Long-term seizure outcome after corpus callosotomy: a retrospective analysis of 95 patients.

Object: The authors report long-term follow-up seizure outcome in patients who underwent corpus callosotomy during the period 1981-2001 at the Montreal Neurological Institute.

Methods: The records of 95 patients with a minimum follow-up of 5 years (mean 17.2 years) were retrospectively evaluated with respect to seizure, medication outcomes, and prognostic factors on seizure outcome.

Morbidity in epilepsy surgery: an experience based on 2449 epilepsy surgery procedures from a single institution.

Object: In this paper the authors aimed to provide information related to major and minor surgical and neurological complications encountered following stereoelectroencephalography and epilepsy surgery.Methods The authors performed a retrospective review of 491 and 1905 patients who underwent intracranial electrode implantation and epilepsy surgery, respectively, between 1976 and 2006 at the Montreal Neurological Institute. All intracranial electrode implantations and surgical procedures were performed by 1 surgeon (A.

Psychosocial outcome after extratemporal epilepsy surgery: a prospective clinical study.

Aim: The purpose of this prospective clinical study was to examine the short- and long-term psychosocial outcomes of a consecutive series of patients who underwent extratemporal lobe resection due to medically-refractory epilepsy.

Materials And Methods: The sample consisted of 23 consecutive patients and all patients completed a questionnaire assessing especially psychosocial outcome 6 months and 2 years after surgery. Results obtained at short- and long-term follow-ups were compared to baseline.

Psychosocial status before and after temporal lobe epilepsy surgery: a prospective clinical study.

Objective: The purpose of this prospective work was to evaluate the relationship between seizure outcome and psychosocial status in patients who underwent temporal lobe epilepsy surgery for medically intractable seizure.

Methods: The Liverpool Psychosocial Battery, which includes physical, social, and psychological domains, was completed by 63 patients with temporal lobe epilepsy before surgery, as well as 6 months and 2 years after surgery. The differences regarding the Liverpool Psychosocial Battery domains were compared between seizure-free and nonseizure-free patients at 6 months and 2 years after surgery.

Long-term seizure outcome after mesial temporal lobe epilepsy surgery: corticalamygdalohippocampectomy versus selective amygdalohippocampectomy.

Object: Resection strategies for the treatment of temporal lobe epilepsy (TLE) are a matter of discussion, and little information is available. The aim of this study was to compare seizure outcomes at the 5-year follow-up in patients with medically refractory unilateral mesial TLE (MTLE) due to hippocampal sclerosis (HS) who were treated using a cortical amygdalohippocampectomy (CorAH) or a selective AH (SelAH).

Methods: The authors obtained data from 100 adult patients who underwent surgery for MTLE.

Life 12 years after temporal lobe epilepsy surgery: a long-term, prospective clinical study.

It has been suggested that aim of the temporal lobe epilepsy surgery is twofold: first is to decrease seizure frequency and second is to improve quality of life without causing intolerable complications. The aim of this prospective, longitudinal clinical study is to report outcomes with respect to seizure, medication, employment and quality of life in short- and long-term follow-ups after resective temporal lobe epilepsy surgery. Consecutively 63 patients who underwent resective temporal lobe epilepsy surgery between 1993 and 1994 were enrolled.

Long-term outcome after surgical treatment of temporal lobe epilepsy in children.

Object: Surgery is an accepted treatment for carefully selected patients with focal epilepsy. In the present study, the authors assessed clinical and surgery-related data obtained in a large series of children suffering from intractable temporal lobe epilepsy (TLE).

Methods: Etiological, pathological, and clinical features of possible prognostic significance were studied in 109 children who underwent surgery for TLE at the Montreal Neurological Institute and Hospital and the Montreal Children's Hospital between 1985 and 2000.

Factors predictive of suboptimal seizure control following selective amygdalohippocampectomy.

Object: Selective amygdalohippocampectomy (SelAH) is used in the treatment of mesial temporal lobe epilepsy (MTLE). The goal of this study was to determine factors predictive of poor postoperative seizure control (Engel Class III or IV) following SelAH.

Methods: A retrospective study was conducted of 27 patients with poor seizure control postoperatively (Engel III/IV group), in comparison with 27 patients who were free from seizures after surgery (Engel I/II group).