Image-guided stereotactic radiosurgery for locally advanced pancreatic adenocarcinoma results of first 85 patients.

Background: Locally advanced unresectable pancreatic adenocarcinoma is characterized by poor survival despite chemotherapy and conventional radiation therapy (RT). Recent advances in real-time image-guided stereotactic radiosurgery (SRS) have made it possible to treat these cancers in two to four fractions followed by systemic chemotherapy.

Aims: The aims of this study includes the following: (1) obtain local control of the disease; (2) improve the survival of these unresectable patients; (3) evaluate the toxicity of SRS; and (4) report results of the largest series from a single center.

The role of vaginal stimulation for the acquisition of conditioned place preference in female Syrian hamsters.

This study investigated the importance of vaginal stimulation on conditioned place preference by sexual behavior in female Syrian hamsters. Hormonally primed female hamsters given vaginal masks and topical lidocaine prior to conditioning sessions were no different in their place preference conditioning compared to female controls with no vaginal mask or lidocaine. Control females not provided a sexually active male did not show any preference for either compartment of the conditioning apparatus.