Publications by authors named "Nicole Noack"

Horse serum is commonly used as an additive to support the maintenance of hematopoietic progenitor cells in culture. However, the wide variability in the performance of different lots calls for parallel testing of multiple batches over extended periods of culture. Identification of the serum components that determine hematopoietic support would therefore save considerable time and effort and would help to standardize culture procedures.

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Hematopoietic bone marrow is a regenerative tissue of high clinical relevance, yet relatively little is known about the metabolism of the stem and progenitor populations concerned. We have used a multipotent murine cell line to generate sufficient numbers of cells undergoing self-renewal, erythroid or myeloid differentiation to allow a proteomics analysis of enriched mitochondria. Stringent analysis identified 37 mitochondria-associated proteins changing on differentiation in this system.

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Objective: Adiponectin plays an important role in pathophysiology of obesity, type 2 diabetes and cardiovascular disease. The aim of this study was to determine adiponectin concentrations in children and adolescents with type 1 diabetes in a longitudinal manner and to study the impact of age, gender, body mass index (BMI) and metabolic control.

Research Design And Methods: In this study, 88 children and adolescents with type 1 diabetes were followed longitudinally.

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Purpose: The purpose of this study was to determine the success of IMZ implants after prosthodontic rehabilitation.

Patients And Methods: A prospective study analysis was made of the treatment results for 541 patients after the insertion of a total of 1,250 IMZ implants at 2 practicing dentists' offices over a period of 13 years. The most frequent treatment situations were insertion in the totally edentulous lower jaw (44.

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The aim of this study was to evaluate the long-term prognosis after insertion of 510 IMZ-implants in case of free-end situations of the upper and lower jaw and prosthodontic restoration. We examined 222 patients prospectively who were treated in a dental practice because of uni- or bilateral free-end situation between 1984 and 1996. Affected and crowned teeth which were neighbouring the implant-based suprastructure, were blocked with these by use of bridge-restorations or attachments.

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