Treatment-Related Uptake of -(2-F-Fluoroethyl)-l-Tyrosine and l-[Methyl-H]-Methionine After Tumor Resection in Rat Glioma Models.

Assessment of residual tumor after resection of cerebral gliomas can be difficult with MRI and may be improved by amino acid PET. The aim of this experimental study was to investigate uptake of 2-F-fluoroethyl-l-tyrosine (F-FET) and l-[methyl-H]-methionine (H-MET) in residual tumor after surgery and possible false-positive uptake in treatment-related changes. F98 or GS-9L rat gliomas were implanted into the brain of 64 rats.