Publications by authors named "Nicole Naccache"

Aims: Conflicting data exists about long-term outcomes in young women and men experiencing acute myocardial infarction (AMI).

Methods: The FAST-MI program consists of three nationwide French surveys carried out 5years apart from 2005 to 2015, including consecutive patients with AMI over a 1-month period with up to 10-year follow-up. The present analysis focused on adults≤50 yo according to their gender.

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Background Quality of Life (QoL) is a prognostic factor in heart failure (HF) of patients with acquired cardiac disease. The aim of this study was to determine the predictive value of QoL on outcomes in adults with congenital heart disease (ACHD) and HF. Methods and Results Quality of life of 196 adults with congenital heart disease with clinical heart failure (HF) (mean age: 44.

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Article Synopsis
  • Surgical aortic valve replacement (SAVR) is recommended for low-risk patients, while the Heart Team should decide between transcatheter aortic valve implantation (TAVI) and surgery for others, with a preference for TAVI in older patients.
  • A multicenter study surveyed 1,049 patients aged 75 and older to understand the role of age and surgical risk in treatment decisions for severe aortic stenosis, finding that TAVI was preferred in 71% of cases.
  • The study revealed that as age increases, particularly after 80, the influence of surgical risk scores on treatment decisions decreases significantly, leading most patients to be referred for TAVI even if they have low surgical risk; however, 10%
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Backgrounds: Optimal pain management in bariatric patients is crucial for early recovery. This study aims to evaluate the effects of magnesium and ketamine combination on morphine consumption after open bariatric surgery (primary outcome), as well as on postoperative pain scores and occurrence of side effects.

Method: A total of 60 patients undergoing elective open gastric bypass were randomized into 3 groups.

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Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are cornerstone in multimodal analgesia protocols. This point is of great value in morbidly obese patients due to the high prevalence of restrictive pulmonary disease and obstructive sleep apnea. The aim of this study was to test the hypothesis that NSAIDs do not increase acute bariatric surgery complications while optimizing postoperative analgesia.

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Article Synopsis
  • The study focuses on customizing treatment for acute postoperative pain based on factors that affect how patients respond to morphine.
  • It involved 95 patients and found that morphine doses were influenced by age, weight, and the length of surgery, with older patients and those undergoing longer surgeries receiving lower doses.
  • Genetic variations in OPRM1 and ABCB1 were also linked to morphine requirements, with certain genotypes needing significantly higher doses compared to others.
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The history of pain is one of the concepts that have divided Cartesian thinkers and mystical philosophers in the Western civilization over centuries. Depending on the historical period, different dogmas and morals intersect, oppose or attempt conciliation. The attitude towards pain evolved with the evolution of mentalities in the broad sense but also by relying on scientific discoveries in the field.

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Opioids remain essential drugs for the treatment of severe cancerous pain. However, many countries have developed new regulations and policies for a better availability and accessibility of these drugs. Lebanon is not too far from these advanced strategies.

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Introduction: Varicocelectomy is a common operation in urology associated with considerable postoperative pain. The aim of this prospective, randomized, double-blind study was to investigate whether a combination of general anesthesia and bilateral nerve stimulator guided paravertebral nerve blocks could provide better postoperative pain relief compared to general anesthesia in combination with placebo paravertebral nerve block.

Methods: Sixty patients scheduled for varicocelectomy were randomized prospectively.

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In this case series, we present the effectiveness of multilevel nerve stimulator-guided paravertebral block (PVB) technique in obese women of body mass index ≥30 kg/m(2) undergoing breast cancer surgery with or without axillary dissection. Twenty-six obese women were included in this case series. Block classification, hemodynamics and complication rate, postoperative nausea and vomiting, postoperative analgesic consumption, post-anesthesia care unit (PACU) stay, and hospital stay were recorded.

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Breast cancer surgery is frequently associated with postoperative nausea, vomiting, pain and painful restricted movement. It is well established that thoracic paravertebral block with or without general anesthesia provides better postoperative analgesia and reduces the risk of nausea and vomiting after breast surgery as well as the incidence of chronic pain. Paravertebral block improves the quality of recovery after breast cancer surgery and provides the patient with the option of ambulatory discharge.

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Pediatric orthopedic surgery is rarely done in an outpatient setting because of the postoperative pain. The purpose of this study was to evaluate the children's comfort and parents' satisfaction after ambulatory peripheral pediatric orthopedic surgery performed under general anesthesia combined with regional anesthesia (RA). Sixty consecutive children were enrolled in this prospective study.

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Opioid analgesics are essential for the management of moderate to severe pain. In spite of their documented effectiveness, opioids are often underutilized, a factor which has contributed significantly to the undertreatment of pain. Many countries have developed true national policies on cancer pain and palliative care, and in others only guidelines for care have been developed.

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Effective delivery of high-quality palliative care requires effective interprofessional team working by skilled healthcare professionals. Palliative care is therefore highly suitable for sowing the seeds of interprofessional team working in early professional undergraduate medical education. Integrating palliative medicine in undergraduate medical education curricula seems to be a must.

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Goal Of The Study: Lumbar microdiscectomy surgery is already performed under spinal anesthesia (SA) in many institutions. The aim of this study is to compare the quality of analgesia and recovery after SA when compared to general anesthesia (GA) after lumbar microdiscectomy surgery.

Methods: Following light sedation, SA is performed with the patient in the left lateral decubitus position, one to two levels above the herniated disc level.

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