Publications by authors named "Nicole Moutot"
Article Synopsis
- The study investigates the role of the vacuolar proton ATPase (V-ATPase) in loading neurotransmitters into synaptic vesicles and its possible involvement in neurotransmitter release.
- The researchers found a direct interaction between the V-ATPase V0 c-subunit and the v-SNARE synaptobrevin, linking V-ATPase function to the process of vesicle membrane fusion.
- Disruption of this interaction reduced the likelihood of neurotransmitter release without affecting the proton pump's activity, suggesting that V-ATPase may serve both proton transport and SNARE-mediated exocytosis functions.
