Efficacy and safety of brexpiprazole in patients with schizophrenia presenting with severe symptoms: analysis of short- and long-term studies.

Background: The treatment of patients with severe schizophrenia symptoms can be complicated and expensive.

Aims: The purpose of this study was to evaluate the short- and long-term effects of brexpiprazole in patients with schizophrenia presenting with severe symptoms.

Methods: Data were pooled from three six-week, randomized, double-blind, placebo-controlled studies and two 52-week, open-label extension studies.