Publications by authors named "Nicole M van der Werff"
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Synopsis of recent research by authors named "Nicole M van der Werff"
- Nicole M van der Werff's recent research primarily focuses on understanding the dormant stages of malaria, particularly the hypnozoites, and the gene-regulatory mechanisms that govern their dormancy and reactivation in the liver environment.
- Her studies have developed innovative detection methods, such as dual-luciferase assays, which enhance the speed and sensitivity of identifying hypnozoites, paving the way for large-scale screening of compounds aimed at preventing malaria relapses.
- Additionally, her work includes insights from animal models, such as rhesus macaques, to investigate the immune responses related to malaria and other infectious diseases, contributing to the broader understanding of vaccine efficacy and disease management.