Clinical Manifestations.

Background: The Alzheimer's Association recommends early screening of Alzheimer's disease and related dementias(ADRD), urging the development of biomarkers and other tools for early risk/detection. However, the general public's willingness to be tested for early ADRD must be considered, particularly among minoritized populations. For example, Black older adults within the United States (U.

An analysis of direct-to-consumer genetic testing portals and their communication of health risk and test limitations.

Direct-to-consumer (DTC) genetic testing has become incredibly popular for assessing health risk related to specific diseases. However, how this risk is conveyed and whether the limitations of the tests are fully communicated can impact how customers interpret results. Through a qualitative content analysis of three different DTC genetic testing online portals, we examine how companies communicate relative and absolute health risks, the extent to which limitations are communicated, and how this information is presented.

The Role of Human Voice in Direct-To-Consumer Health Communication.

Despite overall positive perceptions, many customers distrust direct-to-consumer genetic testing companies in regard to privacy and aftercare. Prior research suggests companies can assuage mistrust by personalizing communication when discussing sensitive health information. This content analysis of customer e-mails ( = 338) investigates the purpose, personalization, and use of the human voice strategy by direct-to-consumer genetic testing companies to gain trust.

How message appeals and prior product use influence information processing, risk perceptions, trust, attitudes, and genetic test purchase intentions.

Within the direct-to-consumer (DTC) genetic test industry, attracting customers can be difficult especially due to the highly sensitive nature of these products. How these tests are communicated to consumers may be one avenue in which companies can impact customer purchase intentions. A 2 (message sidedness: one-way vs.

Asymmetric chromatin retention and nuclear envelopes separate chromosomes in fused cells in vivo.

Hybrid cells derived through fertilization or somatic cell fusion recognize and separate chromosomes of different origins. The underlying mechanisms are unknown but could prevent aneuploidy and tumor formation. Here, we acutely induce fusion between Drosophila neural stem cells (neuroblasts; NBs) and differentiating ganglion mother cells (GMCs) in vivo to define how epigenetically distinct chromatin is recognized and segregated.

Testing how different narrative perspectives achieve communication objectives and goals in online natural science videos.

Communication of science through online media has become a primary means of disseminating and connecting science with a public audience. However, online media can come in many forms and stories of scientific discovery can be told by many individuals. We tested whether the relationship of a spokesperson to the science story being told (i.

Maternal and perinatal outcomes of indicated inductions of labor.

Purpose: The purpose of this study was to evaluate the labor characteristics and maternal/perinatal consequences following indicated induction of labor.

Methods: This retrospective study examined all of the indicated inductions over 24 months and at two institutions evaluated mode of delivery (vaginal versus cesarean) as well as a comprehensive list of labor characteristics and maternal/perinatal outcomes.

Results: There were 1577 indicated inductions with 1097/1577 (69.

Major depression among methamphetamine users entering drug treatment programs.

Objective: To determine the prevalence of major depression among people entering treatment for methamphetamine use.

Design, Setting And Participants: The study was a cross-sectional survey involving 41 specialised drug and alcohol treatment agencies in Brisbane and Sydney. Services provided by these agencies included residential rehabilitation, detoxification and counselling.

The influence of depression on treatment for methamphetamine use.

Objective: To determine whether the presence of comorbid depression influences response to psychological treatment for methamphetamine use.

Design: Randomised controlled clinical trial.

Setting And Participants: Our study was conducted between 2001 and 2005 at two sites in Australia: the Hunter Region of New South Wales and the city of Brisbane, Queensland.