Publications by authors named "Nicole M Lane Starr"
Article Synopsis
- The study investigates the skin microbiome in pediatric patients with mild atopic dermatitis (AD), comparing it to age- and sex-matched controls while focusing on bacterial strains and metagenomic differences.
- Significant changes were found in the composition of bacteria, particularly Staphylococci, between the AD and control groups, with specific strains exhibiting distinct toxin production.
- The findings suggest that these strain-level variations in toxins may impact human keratinocyte function and could be relevant to the development and management of atopic dermatitis.
Background: The recall periods and response scales of existing surveys of asthma control are poorly suited for studying acute exacerbations.
Objective: To develop an instrument able to predict exacerbations after the onset of acute symptoms and with a recall window sufficiently short to study recovery.
Methods: We developed the six-item Acute Asthma Exacerbation Survey (AAES).
Background: Symptom intensity during a common cold is highly variable, particularly after the illness peaks, contributing to delay in recovery. Rhinoviruses frequently cause colds and, during acute infections, generate leukotriene B4 and prostaglandin E2 (PGE2). PGE2 is known to initiate oxylipin class switching and resolution of acute inflammation.
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