Your diagnosis will not protect you (and neither will academia): Reckoning with education and Dis-Ease.

This article is an autoethnographic exploration of institutionalized responses to uncontrolled substance use informed by medical paradigms. Theoretically, it is situated within a lineage of work in critical drug and Mad studies that challenge assumptions about choice, including - and especially - by interrogating the extent to which choice is an apt conceptual tool for making sense of "addiction." Throughout, I focus on two discrete but analogous events, both of which entailed binging on substances, entering altered states, and being rejected from academic spaces through a lens of biomedicine.

Diagnostic journey and impact of enzyme replacement therapy for mucopolysaccharidosis IVA: a sibling control study.

Background: Mucopolysaccharidosis (MPS) IVA, also known as Morquio A syndrome, is a rare autosomal recessive lysosomal storage disorder caused by a deficiency in the enzyme N-acetylgalactosamine-6-sulfatase. Early recognition, diagnosis, and treatment of this progressive, multisystem disease by enzyme replacement therapy (ERT) can lead to improved outcomes and reduced mortality.

Methods: This report documents the diagnostic journey and treatment with ERT of three siblings with MPS IVA.

Newborn Screening for Pompe Disease: Pennsylvania Experience.

Pennsylvania started newborn screening for Pompe disease in February 2016. Between February 2016 and December 2019, 531,139 newborns were screened. Alpha-Glucosidase (GAA) enzyme activity is measured by flow-injection tandem mass spectrometry (FIA/MS/MS) and full sequencing of the GAA gene is performed as a second-tier test in all newborns with low GAA enzyme activity [<2.

Income generation and attitudes towards addiction treatment among people who use illicit drugs in a Canadian setting.

Introduction: Socioeconomically marginalized people who use illicit drugs (PWUD) often engage in alternative income generating activities to meet their basic needs. These activities commonly carry a number of health and social risks, which may prompt some PWUD to consider addiction treatment to reduce their drug use or drug-related expenses. We sought to determine whether engaging in certain forms of income generation was independently associated with self-reported need for addiction treatment among a cohort of PWUD in Vancouver, Canada.

The Rise and Stall of Canada's Gender-Equity Revolution.

The growing symmetry in gender roles is a revolutionary change as consequential as technological advances and globalization. We illustrate how the social world in Canada has changed for women and men over the course of the last century, both in terms of greater gender equity and of policies supporting equity. However, some of the significant changes that occurred in the last 100 years have recently stalled, while the overall progress has been uneven for certain subgroups.