Publications by authors named "Nicole L Stott Bond"
Biomedicines
December 2022
Article Synopsis
- Lung cancer has a low survival rate (~19% over 5 years), with 80-85% of cases classified as Non-Small Cell Lung Cancer (NSCLC).
- A study tested metformin, a common diabetes medication, on NSCLC cells in the lab and found that it significantly reduced cancer cell growth markers like HES1 and Ki-67.
- The results suggest that metformin could be a promising anti-cancer treatment, warranting further research in real-life models for its potential use in treating NSCLC.
Biomedicines
November 2021
Article Synopsis
- * A study using C57BL/6J mice injected with Lewis lung cancer aimed to evaluate the effects of metformin on tumor burden and skeletal muscle health; however, metformin did not significantly reduce tumor size or improve muscle health.
- * The findings suggest that while metformin shows some anti-cancer effects in other types of cancer, it may not be effective as a standalone treatment for NSCLC, indicating the need for future research on combined treatment approaches.
