Racial disparities in gestational weight gain and adverse pregnancy outcomes among Black and White pregnant people with obesity.

Objective: This study of pregnant people with obesity examined two aims in testing the hypothesis that the COVID-19 pandemic widened racial disparity in maternal health in high-risk pregnancies; it compared by race both (1) gestational weight gain (GWG) patterns and (2) patterns of preexisting conditions and adverse pregnancy outcomes.

Methods: This retrospective chart review included birth certificate and delivery records from a large women's specialty hospital in Louisiana between 2018 and 2022. Differences in preexisting conditions, GWG, and adverse pregnancy outcomes were explored across early-, peak-, and late-pandemic periods using log-linear regression and robust Poisson models.

Trends in Gestational Weight Gain in Louisiana, March 2019 to March 2022.

Importance: Average gestational weight gain (GWG) increased during the COVID-19 pandemic, but it is not known whether this trend has continued.

Objective: To examine patterns of GWG during the COVID-19 pandemic by delivery and conception timing through the second year of the pandemic.

Design, Setting, And Participants: This cohort study is a retrospective review of birth certificate and delivery records from 2019 to 2022.

Correlates of Adolescent Ambiguity in Defining their Experience of Sexual Victimization in Two Large-Scale Croatian Samples.

Adolescents are at increased risk for sexual victimization compared to other age groups and sexual abuse in adolescence is associated with negative health outcomes in adulthood. Sexual experiences are often conceptualized as either consensual or coercive so little is known about adolescents who are unsure whether their negative experience constitutes sexual abuse. The present study used two samples ( = 2235,  = 1253) of Croatian adolescents to explore the psychosocial characteristics and sexualized behaviors associated with difficulty in defining negative sexual experiences.

Pain, Cannabis Species, and Cannabis Use Disorders.

Objective: The purpose of this study was to examine whether individuals who used medical cannabis for chronic pain were at increased risk for cannabis use problems compared with individuals who used medical cannabis for other reasons (e.g., anxiety, insomnia, and muscle spasms).

Sexual function during bupropion or paroxetine treatment of major depressive disorder.

Objective: The primary objective was to evaluate sexual function (SF) separately in men and women with major depressive disorder (MDD) before and during treatment with bupropion sustained release (SR) or paroxetine. The secondary objectives involved a comparative evaluation of the Sex Effects Scale (Sex FX) and the Investigator-Rated Sexual Desire and Functioning Scale (IRSD-F), as well as a comparison of antidepressant outcomes and an examination of the relation between level of depression and SF over time.

Method: There were 141 patients (68 women and 73 men) who met DSM-IV criteria for a current major depressive episode.

The 5-factor model of personality and antidepressant medication compliance.

Objective: Medication noncompliance is a significant problem for effective pharmacologic treatment of major depressive disorder (MDD). Attempts to explore predictors of compliance have primarily focused on demographic characteristics; for the most part, these have been shown to be unrelated to compliance. Conversely, the relation between personality characteristics and compliance has been relatively understudied.

Patient attitudes regarding causes of depression: implications for psychoeducation.

Objective: Patient attitudes toward mental illness are an important determinant of treatment compliance and treatment outcome. A patient's age, sex, style of thinking, lifestyle, and beliefs all may influence perceptions. This study aimed to determine patient attitudes.

Lithium carbonate versus cognitive therapy as sequential combination treatment strategies in partial responders to antidepressant medication: an exploratory trial.

Background: Partial antidepressant response is associated with increased rates of relapse. Despite increasing evidence that full symptomatic remission is the optimal goal of antidepressant therapy, there have been few comparisons between disparate treatment approaches to achieve this goal.

Method: Forty-four patients with DSM-IV major depressive disorder (MDD) who had a partial response (17-item Hamilton Rating Scale for Depression [HAM-D-17] score of 8-15) during open-label antidepressant treatment for 8 to 14 weeks were randomly assigned to receive cognitive therapy (CT) or lithium augmentation (LA) for a further 8 weeks using a single-blind design.

Reboxetine: a preliminary report on its use through the Special Access Program.

Objective: To describe the effectiveness and tolerability of reboxetine under Special Access Program conditions in Canada in a group of patients with refractory depressive disorders.

Design: Retrospective open-label study.

Setting: Six clinical academic settings in Canada, primarily tertiary institutional settings.

Combining antidepressants for treatment-resistant depression: a review.

Objective: Many patients with depression remain poorly responsive to antidepressant monotherapy. One approach for managing treatment-resistant depression is to combine antidepressants and to capitalize on multiple therapeutic mechanisms of action. This review critically evaluates the evidence for efficacy of combining antidepressants.