Publications by authors named "Nicole Joy Bassous"

Article Synopsis
  • Periodontitis is a chronic inflammatory disease caused by bacteria that currently has limited treatment options, mainly slowing its progression.
  • Researchers introduced a new solution using 3D printed bilayer membranes designed for dual-drug delivery and support tissue regeneration, utilizing nanocomposite hydrogels with antimicrobial properties.
  • These membranes showed strong mechanical properties, sustained drug release, and the ability to promote bone regeneration and reduce inflammation, offering a promising advance in periodontitis treatment.
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Noninvasive monitoring of biofabricated tissues during the biomanufacturing process is needed to obtain reproducible, healthy, and functional tissues. Measuring the levels of biomarkers secreted from tissues is a promising strategy to understand the status of tissues during biofabrication. Continuous and real-time information from cultivated tissues enables users to achieve scalable manufacturing.

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In additive manufacturing, bioink formulations govern strategies to engineer 3D living tissues that mimic the complex architectures and functions of native tissues for successful tissue regeneration. Conventional 3D-printed tissues are limited in their ability to alter the fate of laden cells. Specifically, the efficient delivery of gene expression regulators (i.

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Herein, we report the design of electrospun ultrathin fibers based on the combination of three different polymers polycaprolactone (PCL), polyethylene glycol (PEG), and gelatin methacryloyl (GelMA), and their potential bactericidal activity against three different bacteria Staphylococcus aureus (S. aureus), Pseudomonas aeruginosa (P. aeruginosa), and Methicillin-resistant Staphylococcus aureus (MRSA).

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