Publications by authors named "Nicole J Cohen"

Background: On 20 September 2022, the Ugandan Ministry of Health declared an outbreak of Ebola disease caused by Sudan ebolavirus.

Methods: From 6 October 2022 to 10 January 2023, Centers for Disease Control and Prevention (CDC) staff conducted public health assessments at five US ports of entry for travellers identified as having been in Uganda in the past 21 days. CDC also recommended that state, local and territorial health departments ('health departments') conduct post-arrival monitoring of these travellers.

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Public health travel restrictions (PHTR) are crucial measures during communicable disease outbreaks to prevent transmission during commercial airline travel and mitigate cross-border importation and spread. We evaluated PHTR implementation for US citizens on the Diamond Princess during its coronavirus disease (COVID-19) outbreak in Japan in February 2020 to explore how PHTR reduced importation of COVID-19 to the United States during the early phase of disease containment. Using PHTR required substantial collaboration among the US Centers for Disease Control and Prevention, other US government agencies, the cruise line, and public health authorities in Japan.

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In January 2020, with support from the U.S. Department of Homeland Security (DHS), CDC instituted an enhanced entry risk assessment and management (screening) program for air passengers arriving from certain countries with widespread, sustained transmission of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19).

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  • Public health investigations in refugee populations are crucial for creating effective interventions due to their unique vulnerabilities and challenges, such as trauma and economic hardship.
  • A review of 288 articles from 2015 to 2018 revealed that most research focuses on mental health and healthcare access, with a majority obtaining consent but limited use of incentives and post-investigation support.
  • The study highlights a lack of community engagement in protocol reviews and suggests the need for best practices in applying ethical principles in refugee health research.
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  • - An estimated 30 million passengers travel on 272 cruise ships globally each year, creating close quarters that can facilitate the spread of respiratory illnesses like COVID-19.
  • - The COVID-19 virus, which was first identified in December 2019, has led to significant outbreaks on cruise ships, especially affecting vulnerable older populations aged 65 and older.
  • - Between February and March 2020, over 800 confirmed COVID-19 cases and 10 deaths were linked to multiple cruise ship voyages, prompting public health officials to recommend a halt to all cruise travel during the pandemic.
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Background: Influenza outbreaks can occur among passengers and crews during the Alaska summertime cruise season. Ill travellers represent a potential source for introduction of novel or antigenically drifted influenza virus strains to the United States. From May to September 2013-2015, the Alaska Division of Public Health, the Centers for Disease Control and Prevention (CDC), and two cruise lines implemented a laboratory-based public health surveillance project to detect influenza and other respiratory viruses among ill crew members and passengers on select cruise ships in Alaska.

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In 2014, the Centers for Disease Control and Prevention conducted conveyance contact investigations for 2 Middle East respiratory syndrome cases imported into the United States, comprising all passengers and crew on 4 international and domestic flights and 1 bus. Of 655 contacts, 78% were interviewed; 33% had serologic testing. No secondary cases were identified.

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Objective: CDC routinely conducts contact investigations involving travelers on commercial conveyances, such as aircrafts, cargo vessels, and cruise ships.

Methods: The agency used established systems of communication and partnerships with other federal agencies to quickly provide accurate traveler contact information to states and jurisdictions to alert contacts of potential exposure to two travelers with Middle East Respiratory Syndrome Coronavirus (MERS-CoV) who had entered the United States on commercial flights in April and May 2014.

Results: Applying the same process used to trace and notify travelers during routine investigations, such as those for tuberculosis or measles, CDC was able to notify most travelers of their potential exposure to MERS-CoV during the first few days of each investigation.

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During the 2014-2016 Ebola virus disease (Ebola) epidemic in West Africa, CDC implemented travel and border health measures to prevent international spread of the disease, educate and protect travelers and communities, and minimize disruption of international travel and trade. CDC staff provided in-country technical assistance for exit screening in countries in West Africa with Ebola outbreaks, implemented an enhanced entry risk assessment and management program for travelers at U.S.

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In 2012, an outbreak of infection with Middle East respiratory syndrome coronavirus (MERS-CoV), was detected in the Arabian Peninsula. Modeling can produce estimates of the expected annual number of symptomatic cases of MERS-CoV infection exported and the likelihood of exportation from source countries in the Middle East to countries outside the region.

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  • The CDC Quarantine Stations provide essential drugs that are either not available or have limited supply in the U.S. for urgent health treatments.
  • A study found that distributing these drugs from quarantine stations saves an average of 6.66 hours per shipment compared to sending them from CDC headquarters in Atlanta.
  • The findings support keeping a decentralized distribution model, emphasizing the benefits of the CDC's regional presence for efficient drug delivery.
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Objective: Colleges are at risk for communicable disease outbreaks because of the high degree of person-to-person interactions and relatively crowded dormitory settings. This report describes the US college student health screening requirements among US resident and international students for tuberculosis (TB) and vaccine-preventable diseases (VPDs) as they relate to the American College Health Association (ACHA) guidelines. Methods/Participants: In April 2012, US college health administrators (N = 2,858) were sent online surveys to assess their respective school's TB screening and immunization requirements.

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  • In May 2014, the first case of Middle East respiratory syndrome coronavirus (MERS-CoV) in the U.S. was identified in a traveler from Saudi Arabia.
  • A study was conducted to assess the transmission risk by evaluating the type and frequency of contacts among health care personnel (HCP), household members, and community contacts, using questionnaires and GPS tracking.
  • Despite the extensive contact with 61 individuals, all tested negative for MERS-CoV, indicating no secondary cases, and highlighting the potential inaccuracy of self-reported contact compared to GPS data.
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  • The CDC Quarantine Stations provide essential drug products for emergency treatment that are not widely available in the U.S.
  • After analyzing shipment records, it was found that using these stations saves an average of 6.66 hours per shipment compared to distributing from a central site in Atlanta.
  • The results support maintaining a decentralized distribution model to enhance the efficiency of lifesaving drug delivery.
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In response to the largest recognized Ebola virus disease epidemic now occurring in West Africa, the governments of affected countries, CDC, the World Health Organization (WHO), and other international organizations have collaborated to implement strategies to control spread of the virus. One strategy recommended by WHO calls for countries with Ebola transmission to screen all persons exiting the country for "unexplained febrile illness consistent with potential Ebola infection." Exit screening at points of departure is intended to reduce the likelihood of international spread of the virus.

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Mexican-style soft cheese known as queso fresco (QF), which is often unpasteurized, has been implicated in outbreaks of foodborne illness in the United States. The U.S.

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  • In December 2013, the first locally-acquired chikungunya virus infections were reported in the Caribbean, with over 55,000 cases noted by May 16, signaling an ongoing outbreak.
  • Researchers developed models to predict potential new locations for CHIKV spread by analyzing travel patterns, local infection rates, and climate factors, identifying several cities that could receive infected travelers.
  • The models indicate a high probability of local transmission in various Caribbean regions, and potential, albeit uncertain, spread to areas in the continental U.S. and beyond, highlighting the usefulness of such modeling for assessing outbreak risks with limited data.
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Background: The Middle East respiratory syndrome coronavirus (MERS-CoV) was discovered September 2012 in the Kingdom of Saudi Arabia (KSA). The first US case of MERS-CoV was confirmed on 2 May 2014.

Methods: We summarize the clinical symptoms and signs, laboratory and radiologic findings, and MERS-CoV-specific tests.

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CDC is investigating reports of potential occupational exposure to human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and Mycobacterium tuberculosis among workers performing preparation and dissection procedures on human nontransplant anatomical materials at a nontransplant anatomical donation center in Arizona. CDC is working with Arizona public health officials to inform persons exposed to these potentially infected materials. Nontransplant anatomical centers around the United States process thousands of donated cadavers annually.

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The global spread of the influenza A(H1N1)pdm09 virus (pH1N1) associated with travelers from North America during the onset of the 2009 pandemic demonstrates the central role of international air travel in virus migration. To characterize risk factors for pH1N1 transmission during air travel, we investigated travelers and airline employees from four North American flights carrying ill travelers with confirmed pH1N1 infection. Of 392 passengers and crew identified, information was available for 290 (74%) passengers were interviewed.

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Objectives: Infrared thermal detection systems (ITDSs) have been used with limited success outside the United States to screen for fever during recent outbreaks of novel infectious diseases. Although ITDSs are fairly accurate in detecting fever in adults, there is little information about their utility in children.

Methods: In a pediatric emergency department, we compared temperatures of children (<18 years old) measured using 3 ITDSs (OptoTherm Thermoscreen, FLIR ThermoVision 360, and Thermofocus 0800H3) to standard, age-appropriate temperature measurements (confirmed fever defined as ≥38.

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US-bound immigrants with suspected non-infectious TB are encouraged to be medically re-evaluated after arrival in the United States. We evaluated the Centers for Disease Control and Prevention's immigrant referral process, designed to facilitate timely post-arrival evaluations. Over 1,200 immigrants with suspected TB arriving during October 1, 2008-September 30, 2010 were identified.

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Background: In 2010, malaria caused approximately 216 million infections in people and 655,000 deaths. In the United States, imported malaria cases occur every year, primarily in returning travelers and immigrants from endemic countries. In 2010, five Plasmodium falciparum malaria cases occurred among crew members of one US commercial airline company (Airline A).

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Organisms, including Vibrio cholerae, can be transferred between harbors in the ballast water of ships. Zones in the Caribbean region where distance from shore and water depth meet International Maritime Organization guidelines for ballast water exchange are extremely limited. Use of ballast water treatment systems could mitigate the risk for organism transfer.

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