A mild treatment strategy for in-vitro fertilisation: a randomised non-inferiority trial.

Background: Mild in-vitro fertilisation (IVF) treatment might lessen both patients' discomfort and multiple births, with their associated risks. We aimed to test the hypothesis that mild IVF treatment can achieve the same chance of a pregnancy resulting in term livebirth within 1 year compared with standard treatment, and can also reduce patients' discomfort, multiple pregnancies, and costs.

Methods: We did a randomised, non-inferiority effectiveness trial.