Publications by authors named "Nicole C Lopes"
To evaluate the urinary biomarkers related to sepsis in preterm newborns (NBs) and to investigate the predictive capacity of these biomarkers for a longer hospital stay. Serum and urine were collected from 27 healthy NBs, 24 NBs with neonatal infection without sepsis and 11 NBs with sepsis for the measurement of sindecan-1, lipocalin associated with urinary neutrophil gelatinase (uNGAL), urinary cystatin-C (uCysC) and urinary kidney injury molecule-1. Levels of uNGAL and urinary cystatin-C were elevated in NBs with sepsis and neonatal infection, and uNGAL was significant predictor of hospital stay longer than 30 days (odds ratio: 1.
View Article and Find Full Text PDFEndothelium-related biomarkers enhanced prediction of kidney support therapy in critically ill patients with non-oliguric acute kidney injury.
Sci Rep
February 2024
Acute kidney injury (AKI) is a common condition in hospitalized patients who often requires kidney support therapy (KST). However, predicting the need for KST in critically ill patients remains challenging. This study aimed to analyze endothelium-related biomarkers as predictors of KST need in critically ill patients with stage 2 AKI.
View Article and Find Full Text PDFArticle Synopsis
- The study aimed to assess how well vascular biomarkers can predict the need for hemodialysis in critically ill COVID-19 patients.
- It involved 58 patients in the ICU, measuring biomarkers like VCAM-1 and angiopoietins upon admission.
- The results indicated that VCAM-1 and the Ang-2/Ang-1 ratio were significant predictors for both dialysis necessity and mortality risk, with specific cutoff values helping to identify high-risk patients.
To evaluate the prediction capacity of urinary biomarkers for death in critically ill patients with COVID-19. This is a prospective study with critically ill patients due to COVID-19 infection. The urinary biomarkers NGAL, KIM-1, MCP-1 and nephrin were quantified on ICU admission.
View Article and Find Full Text PDF