Publications by authors named "Nicole Alayo"
PLoS Pathog
September 2024
Article Synopsis
- * Resistance mutations in the β-glucan synthase genes (FKS1 and FKS2) are linked to treatment failures, but other unidentified factors influence echinocandin susceptibility.
- * Research on C. glabrata in mice treated with caspofungin revealed rapid genetic changes, including mutations in the FEN1 gene that increase resistance by affecting phytosphingosine levels, which also occurs in clinical strains.
