Endocrine mucin-producing sweat gland carcinoma: a systematic review and meta-analysis.

Background: Endocrine mucin-producing sweat gland carcinoma is a rare, under-reported cutaneous adnexal tumor that is often misdiagnosed and has an unknown incidence of metastasis.

Objective: To determine the incidence of metastasis and tumor recurrence, as well as diagnostic accuracy and current trends in treatment modality.

Methods: A search was performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.

A case of Gerstmann-Straussler-Scheinker (GSS) disease with supranuclear gaze palsy.

Background: Gerstmann-Straussler-Scheinker disease (GSS), an autosomal dominant prion disorder, usually presents as a slowly progressive cerebellar ataxia followed by later cognitive decline. We present a member of the GSS Indiana Kindred with supranuclear palsy, a less common feature in GSS.

Case Presentation: A 42-year-old man presented with 12 months of progressive gait and balance difficulty.