Mandatory immunization: the point of view of the French general population and practitioners.

This survey studies the opinion of the French general population, general practitioners and pediatricians regarding mandatory immunization. Data were collected through standardized telephone questionnaires administered to representative samples of the French population (n=4112) and of French general practitioners and pediatricians (1285 general practitioners (GPs) and 742 pediatricians). 56.

Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: cohort study.

Objective: To assess the safety and effectiveness of eflornithine as first line treatment for human African trypanosomiasis.

Design: Cohort study.

Setting: Control programme in Ibba, southern Sudan.

[Near-total ear amputation: anatomical bases and management].

Background: In cases of near-total ear avulsions, replantation is often successful without microsurgery. The purpose of our study was to investigate the relevant vascular anatomy associated for ear survival.

Patients And Methods: Four cases of successful surgical intervention in near-total ear avulsions are presented.

Inositol 1,4,5 trisphosphate receptor and chromogranin B are concentrated in different regions of the hippocampus.

Calcium (Ca(2+)) release from intracellular stores plays a crucial role in many cellular functions in the brain. These intracellular signals have been shown to be transmitted within and between cells. We report a non-uniform distribution of proteins essential for Ca(2+) signaling in acutely prepared brain slice preparations and organotypic slice cultures, both made from rat hippocampus.

Elevated circulating levels of matrix metalloproteinase-9 in type 1 diabetic patients with and without retinopathy.

Objective: Tissue expression pattern of matrix metalloproteinases (MMPs) and their inhibitors TIMPs indicate that microvascular complications of diabetes mellitus are associated with extracellular matrix remodelling. We investigated whether circulating levels of MMP-9 and TIMP-1 are altered in diabetic retinopathy and whether they might serve as biological markers of ocular complications in type 1 diabetes.

Research Design And Methods: We recruited 47 type 1 diabetic patients free of vascular complications (n=40) or with retinopathy (n=14).