Publications by authors named "Nicolas Traversier"
High risk human papillomavirus prevalence and genotype distribution in Reunion Island.
Eur J Obstet Gynecol Reprod Biol
October 2024
Article Synopsis
- The study aimed to evaluate the prevalence and types of human papillomavirus (HPV) in Reunion Island over a one-year period from 2020 to 2021.
- The overall HPV prevalence was found to be 14.5%, with the most common HPV types being clusters 56, 59, and 66, along with types 16 and 52; notably, vaccine-covered HPV types were present in over half of the HPV-positive cases.
- The research concluded that HPV types in the vaccine are most prevalent and linked to severe cervical issues, emphasizing the need to improve vaccination rates on the island to combat cervical cancer effectively.
Background: Dengue is a major public health concern in Reunion Island, marked by recurrent epidemics, including successive outbreaks of dengue virus serotypes 1 and 2 (DENV1 and DENV2) with over 70,000 cases confirmed since 2017.
Methodology/principal Findings: In this study, we used Oxford Nanopore NGS technology for sequencing virologically-confirmed samples and clinical isolates collected between 2012 and 2022 to investigate the molecular epidemiology and evolution of DENV in Reunion Island. Here, we generated and analyzed a total of 499 DENV1, 360 DENV2, and 18 DENV3 sequences.
Article Synopsis
- - In 2023, dengue virus serotype 2 (DENV2) spread widely across French overseas territories, with over 30,000 suspected cases in the French Caribbean by March 2024.
- - Genome analysis shows that the DENV2 lineage in the Caribbean is now also found in French Guiana and has led to local cases in mainland France, but not in Réunion.
- - To prevent the further spread of the virus and its introduction in new areas, ongoing molecular monitoring and mosquito control efforts are crucial.
Article Synopsis
- HPV is linked to various cancers, particularly cervical cancer, which has a higher incidence on Reunion Island compared to mainland France, highlighting the need for improved vaccination and screening efforts.
- The RUN-SurV-HPV study aims to explore the prevalence of different HPV genotypes among the young population at risk, examining factors like gender and anatomical sites.
- The research will analyze samples from 1200 patients aged 16 to 30, collected during routine STI testing from 2020 to 2022, to better understand HPV risks and support vaccination initiatives.
The Coronavirus 2019 (COVID-19) pandemic has had a considerable impact on the incidence of severe community-acquired pneumonia (CAP) worldwide. The aim of this study was to assess the early impact of the COVID-19 pandemic in the Reunion Island. This multicenter retrospective observational study was conducted from 2016 to 2021 in the hospitals of Reunion Island.
View Article and Find Full Text PDFClinical, epidemiologic, and microbiologic analyses revealed emergence of 26 cases of Corynebacterium diphtheriae species complex infections on Réunion Island, France, during 2015-2020. Isolates were genetically diverse, indicating circulation and local transmission of several diphtheria sublineages. Clinicians should remain aware of the risk for diphtheria and improve diagnostic methods and patient management.
View Article and Find Full Text PDFLittle is known about localized osteoarticular Scedosporiosis (LOS). Most data come from case reports and small case series. Here we present an ancillary study of the nationwide French Scedosporiosis Observational Study (SOS), describing 15 consecutive cases of LOS diagnosed between January 2005 and March 2017.
View Article and Find Full Text PDFCombined incentive actions, focusing on primary care professionals, to improve cervical cancer screening in women living in socioeconomically disadvantaged geographical areas: a study protocol of a hybrid cluster randomised effectiveness and implementation trial- RESISTE.
BMJ Open
November 2022
Article Synopsis
- Cervical cancer (CC) is a leading cause of death that predominantly arises from HPV infections, and underserved women face higher risks due to lower screening rates.
- A cluster randomized trial will assess the impact of financial incentives and different self-sampling return methods on increasing HPV screening rates among 10,000 women aged 30-65 in deprived areas of France.
- The study has received ethical approval, requires no formal consent, and will collect follow-up data through the National Health Insurance to evaluate if incentives can raise HPV self-sampling return rates by at least 10%.
At this time, the literature reports only one case of superinfection with Panton-Valentine leukocidin (PVL)-producing in a patient with severe acute respiratory distress syndrome secondary to coronavirus 2 (SARS-CoV-2) pneumonia. Here we report the first two cases of PVL-producing healthcare-associated pneumonia in patients hospitalized for SARS-CoV-2 pneumonia in the Indian Ocean region. The two isolated strains of S.
View Article and Find Full Text PDFArticle Synopsis
- The study focused on gonococcal arthritis (GA), a rare but significant extra-genital manifestation of gonococcal infection, analyzing cases in Reunion Island from 2008 to 2020.
- A total of 58 cases were identified, predominantly among older men, with most cases linked to recent travel abroad, and while only a small percentage presented genital symptoms, many had other extra-genital manifestations, especially skin lesions.
- The research highlighted the importance of early diagnosis and effective treatment to prevent joint damage, noting that PCR testing can enhance detection in cases where cultures are negative.
Purpose: No data are available on severe community-acquired pneumonia (CAP) in the French overseas department of Reunion Island. This is unfortunate as the microorganisms responsible for the disease are likely to differ from those in temperate regions due to a tropical climate and proximity to other islands of the Indian Ocean region. The aim of this study was to assess the epidemiological, clinical, prognosis, and microbiological characteristics of patients with severe CAP in Reunion Island.
View Article and Find Full Text PDFSince 2018, a dengue epidemic has been ongoing in the French overseas department of Reunion Island, in the Indian Ocean, with more than 25,000 serologically confirmed cases. Currently, three dengue serotypes have been identified in Réunion Island (DENV-1, DENV-2, and DENV-3) progressing in the form of epidemic outbreaks. This arbovirus is mainly transmitted by mosquitoes of the genus Aedes and may be responsible for serious clinical forms.
View Article and Find Full Text PDFThis study aimed to evaluate the incidence of co-infection with different types of pathogens in patients with hypoxemic pneumonia due to coronavirus disease 2019 (COVID-19) in Reunion Island.This observational study using a prospectively collected database of hypoxemic pneumonia due to COVID-19 cases was conducted at Félix Guyon University Hospital in Reunion Island, France.Between 18 March 2020 and 15 April 2020, 156 patients were admitted to our hospital for COVID-19.
View Article and Find Full Text PDFInfection with Leptospira spp. is common in Réunion, a tropical island in the Indian Ocean. However, respiratory coinfections between strains of Leptospira spp.
View Article and Find Full Text PDFObjective: To identify the differential diagnoses of severe COVID-19 and the distinguishing characteristics of critically ill COVID-19 patients in Reunion Island to help improve the triage and management of patients in this tropical setting.
Methods: This retrospective observational study was conducted from 11 March to 4 May 2020 in the only intensive care unit (ICU) authorised to manage COVID-19 patients in Reunion Island, a French overseas department located in the Indian Ocean region. All patients with unknown COVID-19 status were tested by polymerase chain reaction (PCR) on ICU admission; those who tested negative were transferred to the COVID-19-free area of the ICU.
Candida auris is an emerging multidrug-resistant yeast that can cause severe infections and spread easily between hospitalized patients, leading to outbreaks in hospital. Here, we report the first four cases of colonization and invasive infection with C. auris reported in the Indian Ocean region.
View Article and Find Full Text PDFBackground: The spread of carbapenemase-producing Enterobacteriaceae (CPE) in the Southwest Indian Ocean area (SIOA) is poorly documented. Reunion Island is a French overseas territory located close to Madagascar and connected with Southern Africa, Indian sub-continent and Europe, with several weekly flights. Here we report the results of the CPE surveillance program in Reunion Island over a six-year period.
View Article and Find Full Text PDFGram-negative bacilli spp., spp., and spp.
View Article and Find Full Text PDFRationale: Very few cases of secondary peritonitis caused by Streptococcus pneumoniae have been described in the literature, and they have been found to occur mostly in patients with predisposing factors. Here, we report the case of an elderly patient who developed pneumococcal peritonitis secondary to perforation of gastroduodenal ulcer.
Patient Concerns: An 82-year-old man was admitted to intensive care unit (ICU) for septic shock with cardiac impairment 1 day after arriving in the Emergency Department.
The spread of carbapenemase-producing Enterobacteriaceae in the Southwest Indian Ocean islands is poorly known. Here we describe an outbreak of colistin-resistant Enterobacter cloacae harbouring bla in the French overseas department of Mayotte. Between October 2015 and January 2017, all isolates of imipenem-non-susceptible E.
View Article and Find Full Text PDFMelioidosis is a disease caused by bacteria called B. pseudomallei. Infections can develop after contact with standing water.
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