Publications by authors named "Nicolas Rouanes"
Article Synopsis
- A study assessed the quality of life (QoL) of people living with HIV in Nouvelle Aquitaine, France, revealing that while 63.5% reported good/very good QoL, significant improvements are still needed.
- The highest QoL scores were in physical and environmental domains (both median 69), while social and psychological scores were notably lower (both median 56).
- Factors like having three or more comorbidities, experiencing HIV-related stigma, and a monthly income below €1500 were linked to poorer QoL, highlighting the need to address both health and social issues to improve outcomes for all PLWH.
Background: To evaluate drug use (alcohol, tobacco, cannabis and other drugs) and its association with mean CD4/CD8 T cell count ratio, a marker of chronic inflammation, in virally suppressed people living with HIV-1 (PLWH) in Nouvelle Aquitaine, France.
Methods: A multi-centric, cross-sectional analysis was conducted in 2018-19 in the QuAliV study-ANRS CO3 AQUIVIH-NA cohort. Tobacco, alcohol, cannabis, and other drug use (poppers, cocaine, amphetamines, synthetic cathinones, GHB/GBL) were self-reported.
Article Synopsis
- - The study aimed to differentiate infectious aortitis (IA) from noninfectious aortitis (NIA) by examining their clinical, biological, and radiological features, along with their outcomes in a retrospective analysis of 183 patients from 10 French centers between 2014 and 2019.
- - Results showed that 36.1% of patients had IA, primarily caused by bacteria like Enterobacterales and streptococci, while NIA was mainly due to vasculitides and idiopathic causes; IA was notably linked to a higher prevalence of aortic aneurysms and lower survival rates.
- - The study concluded that IA had significantly higher mortality compared to NIA, with effective initial antibiotic treatment being
We aimed to estimate the prevalence of depressive disorder in people living with HIV (PLWH) and evaluate its association with non-HIV-specific and HIV-specific factors in PLWH and in PLWH compared to the general population (GP). We used cross-sectional data from the QuAliV study, conducted within the ANRS-CO3 Aquitaine-AQUIVIH-NA cohort of PLWH in Nouvelle-Aquitaine (2018-2020), and a nationally-representative survey in the GP (EHIS-ESPS, 2014-2015), we included all participants aged ≥ 18 years old who had completed the Patient Health Questionnaire-8 (PHQ-8). Depressive disorder was defined as Patient Health Questionnaire-8 score greater or equal to 10.
View Article and Find Full Text PDFBackground: Antiretroviral therapy has prolonged the lives of those with human immunodeficiency virus (HIV), but the effects of chronic infection on their health-related quality of life (HRQoL) remain a concern. Numerous instruments have been developed to measure HRQoL, yet evidence of their cross-cultural equivalence and continued applicability is limited. We adapted the WHOQOL-HIV BREF to French and assessed its psychometric properties in a sample of community-dwelling adults living with HIV who were mostly virally suppressed.
View Article and Find Full Text PDFDalbavancin is a glycopeptide antibiotic with a long half-life, recently marketed in Europe for skin and soft-tissue infections (SSTIs), but its real-life use is not well known. The aim of this study was to describe all first prescriptions in France over an 16-month period. A retrospective study on all adult patients receiving at least one dose of dalbavancin from 1 June 2017 to 31 September 2018 was performed (75 patients from 29 French hospitals).
View Article and Find Full Text PDFObjective: To report efficacy and tolerance of interleukin 1 blockade in adult patients with mevalonate kinase deficiency (MKD).
Methods: We retrospectively collected data on 13 patients with MKD who had received anakinra (n = 10) and canakinumab (n = 7).
Results: Anakinra resulted in complete or partial remission in 3/10 and 5/10 patients, respectively, and no efficacy in 2/10, but a switch to canakinumab led to partial remission.