Publications by authors named "Nicolas Morel Journel"

Objectives: To report the surgical outcomes and complications experienced after implantation of the ZSI475 FtM prosthesis after phalloplasty.

Methods: All consecutive patients who underwent ZSI475FtM prosthesis implantation in their neophallus between January 2016 and March 2024 in our center were included. There was no exclusion criterion.

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Background: Urethral strictures post-hypospadias repair in adults is one of the most complex subjects in urethral reconstruction. Our goal is to provide an overview of the challenges encountered and the current treatment options.

Methods: A comprehensive literature review was conducted using PubMed for the period from 2020 to 2023.

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Background: Urethral strictures are a common and persistent pathology in urology with significant clinical repercussions. Our aim is to provide an overview of the general aspects of this condition.

Methods: A comprehensive review of the literature from PubMed was conducted covering the period from 2020 to 2023.

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Background: The diagnosis of urethral strictures logically includes a precise assessment of urinary symptoms, but must also take into account the impact on sexuality. What role will new imaging play in 2024?

Methods: A literature review from December 2020 to December 2023 was carried out, combined with a synthesis of the recommendations of the American, Canadian, European and French urology associations. References from these recommendations were also used.

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Objective: The aim of the present report was to provide an up-to-date overview of the existing literature on female urethral stricture (FUS) including its definition, epidemiology, risk factors, diagnostic and therapeutic approaches.

Methods: A literature search was conducted in January 2024 using the MedLine and Embase databases, screening for randomized controlled trials (RCTs), prospective and retrospective series and reviews on female urethral stricture.

Results: Urethral stricture is a rare occurrence in female patients.

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This article aims to summarize the current knowledge on the evaluation and follow-up of urethral stricture (US) treatments through a comprehensive literature review and to propose a detailed follow-up protocol post-treatment. There is no consensus on how to assess US treatments. It must address both anatomical factors (evaluated by the urologist) and functional factors (evaluated by the patient).

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Article Synopsis
  • - The article focuses on Posterior Urethral Stenosis (PUS), discussing the surgical challenges and summarizing current management practices based on a review of literature and recommendations from key urological associations.
  • - The review highlights different types of PUS, such as those resulting from pelvic fractures, benign prostatic hyperplasia (BPH), prostatectomy, and radiotherapy, each presenting unique treatment challenges and risks.
  • - Treatment strategies for PUS are varied and should be tailored to the specific location and cause of the stenosis, balancing surgical options with the patient’s overall health and the potential impacts on urinary and sexual functions.
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Introduction: Distal anterior urethral strictures (DAUS) affect the meatus, navicular fossa (NF) and penile urethra (PU). The main causes are inflammatory (lichen sclerosous [LS]), traumatic iatrogenic, or idiopathic. Post-hypospadias stenosis is common and constitutes a separate entity, dealt with in a separate article.

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Background: Bulbar urethral strictures are the most frequently encountered. Their management is standardized and needs to be applied to improve results.

Methods: A comprehensive literature review was conducted from December 2020 to December 2023, combined with a summary of recommendations from the American, Canadian, European, and French urological associations.

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Background: A significant proportion of trans women is demanding for a genital gender-affirming surgery, with vulvo-vaginoplasty being the most frequently requested procedure. The gold standard for primary vaginoplasty in trans women is the penile skin inversion technique with scrotal skin graft, which allows for increased depth of the vaginal cavity.

Aims: The assessment of vulvo-vaginoplasty outcomes utilizing penile skin inversion and scrotal skin graft in individuals assigned male at birth in the surgeon's learning curve involves evaluating aesthetics, functionality, and sexual aspects.

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Introduction: Gynecological primary care is a public health issue, however, there is no French data on the transmasculine population, despite identified needs and a low coverage rate described in the international literature. The objective was to analyze the access of the French transmasculine population to gynecological primary care.

Methods: The study "Trans men and Transmasculine non-binary individuals use and access to prevention and sexual health care 2022" is a non-interventional, self-administrated, anonymous online study targeting transmasculine adults living in France.

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Article Synopsis
  • - The study evaluates the outcomes of supra-pubic phalloplasty (SPP) in terms of sexuality, urinary function, and overall patient satisfaction, focusing on data collected from patients treated between 2007 and 2018.
  • - A total of 77 patients participated, with 33 responding to questionnaires; results indicated high satisfaction levels, a mean neophallus length of 15.3 cm, and favorable sexual and urinary function outcomes.
  • - The findings suggest that pre-expanded SPP is an effective technique, providing significant improvements in appearance and function, along with a high rate of satisfaction regarding the phalloplasty experience.
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Pelvic fracture (PF) is a rare emergency, which led to pelvic fracture urethral injury (PFUI) in 1.6% to 25% of cases. Urethral injury assessment requires a thorough analysis of the initial injury history and imaging that combine cystourethrography acutely, repeat urethral imaging as well as adjunctive use of MRI in the follow-up period.

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Introduction: The Operated Male-to-Female Sexual Function Index (oMtFSFI) questionnaire is the first scoring system developed to assess sexual function after gender-affirming vulvo-vaginoplasty, and was initially developed and validated in Italian. The aim of this study was to provide linguistic validation of the questionnaire in French through several steps including use of the questionnaires across a series of patients who had undergone gender-affirming vulvo-vaginoplasty between 2020 and 2022 at two French academic centers.

Method: The French version of the oMtFSFI questionnaire was obtained through a double translation (Italian to French) and a back-translation (French to Italian), validated by a scientific committee, and cognitively assessed by a panel of expert patients.

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Introduction: The objective of this study is to make an inventory of surgical practices and their consequences in the short and medium term on sexuality and micturition comfort.

Materials And Methods: It is a retrospective multicenter study over ten years on 63 men who had an operation for a fracture of the corpora cavernosa associated or not with a urethral lesion. Patient history, clinical presentation, surgical management as well as postoperative data were collected from operative reports.

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Objective: To perform a systematic review and meta-analysis of endoscopic procedures for treating vesico-urethral anastomotic stenosis (VUAS) after prostatectomy, as initial VUAS management remains unclear.

Methods: A search of the MEDLINE database, the Cochrane database, and clinicaltrials.gov was performed (last search February 2023) using the following query: (['bladder neck' OR 'vesicourethral anastomotic' OR 'anastomotic'] AND ['stricture' OR 'stenosis' OR 'contracture'] AND 'prostatectomy').

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Objective: To analyze surgical and functional outcomes of bilateral pedicled scrotal flaps for penile shaft reconstruction.

Materials And Methods: A retrospective analysis was performed on 22 patients who underwent penile shaft reconstruction with bilateral pedicled scrotal flaps between 2009 and 2017. Demographics, peri-operative data, and surgical complications were collected.

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Article Synopsis
  • Cryopreservation of ovarian tissue is crucial for preserving fertility in girls and women undergoing treatments that may harm their reproductive capabilities, with slow freezing and vitrification as two main methods evaluated.
  • A study divided ovarian tissue into three groups: fresh, slow freezing, and vitrification, analyzing follicular density, quality, and gene expression.
  • Results showed no significant difference in follicular density or histological quality between the methods, but slow freezing negatively impacted primordial follicle health and specific gene expressions related to steroidogenesis and cell cycle regulation compared to fresh tissue.
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Objective: To evaluate the surgical and functional outcomes of urethral reconstruction associated with phalloplasty, depending on the surgical techniques and patient history.

Materials And Methods: We conducted a single-centre retrospective study including 89 patients who underwent phalloplasty with urethral reconstruction between 2007 and 2018. Patients included were trans-male patients undergoing gender-affirming surgery and cis-male patients undergoing penile reconstruction after trauma, congenital malformation, or cancer.

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The inferior epigastric artery (IEA) is commonly used as a recipient vessel in microsurgical phalloplasty but its use can be associated with abdominal parietal complications (hernia, bulging). To preclude such complications and avoid involvement of the femoral artery, we assessed an external pudendal artery (EPA) as a recipient vessel. We studied the disposition of the external pudendal system and its general anatomy.

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Purpose: Evaluate the surgical outcomes along with a comprehensive assessment of functional outcomes in cis men (non-trans) who underwent phalloplasty.

Methods: All consecutive cis men who underwent phalloplasty from 2008 to 2018 for penile insufficiency due to various causes were included. These underwent phalloplasty by either a radial forearm free flap (RFFF) or suprapubic phalloplasty (SPP).

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Background: Simple cystectomy with urinary diversion is the favored option for treating conditions responsible of neurogenic bladder dysfunction after failure of conservative treatments. Despite the existence of validated assessment tools, the impact of cystectomy on female sexual function remains scarcely investigated.

Aim: The aim was to assess the sexual function and body image of female patients who underwent urinary diversion for a nonmalignant condition and to investigate the factors that may influence sexual life quality.

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