Successful treatment of metastatic refractory gestational choriocarcinoma with pembrolizumab: A case for immune checkpoint salvage therapy in trophoblastic tumors.

•Cure rates are high for choriocarcinoma, however chemoresistant disease often leads to death.•High expression of PD-L1 suggests a role for checkpoint inhibitors in choriocarcinoma.•Pembrolizumab should be considered for salvage therapy for chemoresistant choriocarcinoma.

A Rare Case of Ovarian Serous Borderline Tumor with Brain Metastasis.

. Serous borderline tumor represents a group of noninvasive tumor of the ovary bridging between benign serous cystadenoma and serous carcinoma. They are commonly seen in younger women and usually have an excellent outcome but seldom show local recurrence (J.

Q Fever Presented as a Large Retroperitoneal Pseudotumoral Mass.

Background: Q fever is an infection caused by , an intracellular organism. Acute infection is most often a benign and asymptomatic process; however, some individuals may go on to develop subacute and persistent localized symptomatic Q fever. As such, the clinical and histopathologic findings of Q fever are widely variable and may be missed if clinical suspicion is not high.

Cardiophrenic lymph node metastasis in low-grade serous ovarian adenocarcinoma.

•Cardiophrenic lymph node metastasis in low-grade ovarian carcinoma is rare.•Two cases presented here identify clinical strategies needing further attention.•Low-grade disease is treated with surgery given high chemotherapeutic resistance.