Publications by authors named "Nicolas Cobo"

Wheat stripe rust (WSR), a fungal disease capable of inflicting severe crop loss, threatens most of global wheat production. Breeding for genetic resistance is the primary defense against stripe rust infection. Further development of rust-resistant wheat varieties depends on the ability to accurately and rapidly quantify rust resilience.

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Temperate fruit and nut crops require distinctive cold and warm seasons to meet their physiological requirements and progress through their phenological stages. Consequently, they have been traditionally cultivated in warm temperate climate regions characterized by dry-summer and wet-winter seasons. However, fruit and nut production in these areas faces new challenging conditions due to increasingly severe and erratic weather patterns caused by climate change.

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Article Synopsis
  • Several resistance genes against Fusarium wilt in strawberries were identified and mapped, allowing for the development of resistant cultivars through marker-assisted selection.
  • The Fusarium oxysporum f. sp. fragariae pathogen significantly threatens strawberry production, causing severe wilting and plant death in susceptible varieties.
  • Resistance to multiple races of the pathogen is widespread in strawberry populations, and further genetic studies are planned to identify the specific genes responsible for this resistance to prevent potential outbreaks.
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Article Synopsis
  • Diploid and octoploid strawberries exhibit significant color variation due to different patterns of anthocyanin accumulation, primarily controlled by the MYB10 transcription factor.
  • Mutations in MYB10 are linked to most of the color variation observed in both woodland and cultivated strawberries, with specific mutations correlating to white-fruited ecotypes losing anthocyanin production.
  • Additionally, genetic analysis revealed that variations in MYB10's regulatory elements impact anthocyanin levels in the fruit, influencing skin and flesh color in octoploid strawberries.
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Background: NAC transcription factors contain five highly conserved subdomains which are required for protein dimerisation and DNA binding. Few residues within these subdomains have been identified as essential for protein function, and fewer still have been shown to be of biological relevance in planta. Here we use a positive regulator of senescence in wheat, NAM-A1, to test the impact of missense mutations at specific, highly conserved residues of the NAC domain on protein function.

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Durum wheat () derives from a hybridization event approximately 400,000 years ago which led to the creation of an allotetraploid genome. The evolutionary recent origin of durum wheat means that its genome has not yet been fully diploidised. As a result, many of the genes present in the durum genome act in a redundant fashion, where loss-of-function mutations must be present in both gene copies to observe a phenotypic effect.

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The appearance of highly virulent and more aggressive races of f. sp. () during the last two decades has led to stripe rust epidemics worldwide and to the rapid erosion of effective resistance genes.

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