Publications by authors named "Nicolae Dragos Margaritescu"

: Ventral hernia repair (VHR) is a common surgical intervention linked to specific surgical site complications. In such occurrences, the related morbidity is often substantial. Although known risk factors have long been recognized, their systematic inclusion in risk stratification systems lacks universal validation.

View Article and Find Full Text PDF

Epstein syndrome is an extremely rare genetic disorder characterized by the association of nephritis, deafness and megathrombocytopenia. We present the case of a 21-year-old patient diagnosed with Epstein syndrome and hyperparathyroidism secondary to chronic kidney disease. The main particularity of this case resides in the association between megathrombocytopenia and secondary hyperparathyroidism requiring surgery, which could lead to a series of concerns regarding the intra- and postoperative hemorrhagic risk of the procedure.

View Article and Find Full Text PDF

Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor originating from the Cajal interstitial cells, immunologically characterized by the c-kit gene. The evolution may be asymptomatic, discovered by chance during a necropsy, upper gastrointestinal endoscopy or due to complications of type-algic, occlusive or hemorrhage. We present the case of a voluminous gastric GIST complicated with serious upper gastrointestinal bleeding in a patient with multiple hard associated diseases, undergoing an emergency surgery in hemorrhagic shock.

View Article and Find Full Text PDF

Aim: The authors assessed the morphological profile of tumor masses belonging to the small bowel discovered in their daily practice.

Materials And Methods: 31 tumor masses located in different segments of small intestine operated between 2002 and 2013 in the 1st Surgical Department, Emergency County Hospital of Craiova, Romania, were analyzed. The investigated parameters were: tumor location and number, tumor dimensions, gross assessment, tumor extension and histological assessment.

View Article and Find Full Text PDF

Chronic venous leg ulcers (VLU), especially long-lasting non-healing ulcers, are among the risk factors for squamous cell carcinoma (SCC). Malignant transformation of a VLU is a rare finding and the relative risk of carcinomatous transformation is quite low (about 5.8).

View Article and Find Full Text PDF
Article Synopsis
  • The authors share their experience with gastrointestinal stromal tumors (GIST), studied through the analysis of 15 cases operated on between 2008 and 2013.
  • Diagnosing GIST preoperatively proved challenging, often identified through complications or imaging, with CT scans aiding in assessing tumor size and location across different parts of the digestive tract.
  • Post-surgery, patients had a low morbidity rate, and while some were cured, others faced recurrence; the combination of surgery followed by adjuvant therapy with Imatinib is crucial for improving outcomes.
View Article and Find Full Text PDF