The prognostic role of microsatellite instability in colorectal cancer patients.

Background: Data from the literature regarding the prognostic role of DNA mismatch repair system (MMR) in colorectal cancer are still controversial.

Aim: The aim of the study was to identify the prognostic role of different phenotypic, clinical and pathological characteristics in microsatellite unstable vs. microsatellite stable colorectal cancer in terms of survival and disease free interval.

Robot-assisted transaxillary thyroid surgery-retrospective analysis of anthropometric features.

Purpose: The vast majority of studies published on robot-assisted thyroid surgery are South Korean. This study aims to assess the impact of certain anthropometric parameters on performing robot-assisted thyroid surgery on Caucasian patients.

Materials And Methods: A total of 91 patients underwent robot-assisted surgery by the axillary approach in the Fifth Surgical Clinic, City Hospital Cluj-Napoca, between 2010 and 2015.

Operative outcomes of robot-assisted transaxillary thyroid surgery for benign thyroid disease: early experience in 50 patients.

Purpose: The main benefits of robot-assisted transaxillary thyroid surgery are to overcome the technical limitations of other endoscopic procedures for this surgical pathology and to avoid any cervical skin incision. This article describes the first experience of a Romanian team with the endoscopic robot-assisted thyroid surgery.

Material And Methods: We used the da Vinci SI intuitive surgical system to carry out 50 thyroid operations: 33 unilateral total lobectomies with isthmectomy (TL), 8 unilateral total lobectomies, with contralateral subtotal lobectomy, and 9 total thyroidectomies.

The role and prognostic impact of lymph node ratio on stage III colorectal cancer.

Aim: The aim of this study was to evaluate the prognostic significance of the lymph node ratio (LNR) in patients with stage III colorectal cancer.

Materials And Methods: We included 35 stage III colorectal cancer patients who underwent a curative resection at the County Clinic Hospital, Cluj-Napoca, 5(th) Surgical Clinic between January 2006-July2008. Patients were categorized into LNR groups 1 to 5 according to cut-off points: <0.

Conventional radiology and right heart catheterization in estimating primary pulmonary hypertension and pulmonary hypertension secondary to left-sided valvular disease.

Aim: to estimate the comparative value of conventional radiology and cardiac catheterization in establishing the diagnosis and severity of primary and secondary pulmonary hypertension. We also tried to achieve some correlations between the radiological and invasive parameters.

Methods: we performed a retrospective study over an 11-years time period, analyzing data from a group of 14 patients diagnosed with primary pulmonary hypertension compared to a matched group of 20 patients suffering from pulmonary hypertension secondary to mitral and aortic valvular disease.

Minimally invasive surgical treatment of morbid obesity in patients with specific comorbidities. A case report.

The mortality of patients with morbid obesity is 2 to 12 times higher according to age, comorbidities and the degree of obesity. Surgical treatment has proved to be the only type of treatment that has led to favorable long-term results. We present the therapeutic strategy used in a 39 year old obese patient with BMI=39.

A rare case of systemic autoimmune disease with intricate features of systemic sclerosis, lupus, polymyositis and rheumatoid arthritis. Overlap syndrome or mixed connective tissue disease?

We report an unusual case of connective tissue disease characterized by the coexistence of signs, symptoms and immunological features of 4 defined autoimmune diseases: systemic lupus erythematosus (SLE), systemic sclerosis (SSc), polymyositis (PM) and rheumatoid arthritis (RA). A 53-year-old female was admitted in our clinic with massive polyserositis (pretamponade) as well as skin, joint, muscular lesions and altered general status. The problem we found was the difficulty of including this case in a known clinical entity; SSc/SLE/PM//RA overlap syndrome and mixed connective tissue disease were the two most plausible diagnoses.