Publications by authors named "Nicola Tomasetti"
Article Synopsis
- Soft tissue sarcomas make up a rare group of tumors accounting for just 1% of solid cancers, with liposarcoma being a notable subtype.
- The study focused on 21 patients with atypical lipomatous tumors/well differentiated liposarcoma (ALT/WDLPS) and dedifferentiated liposarcoma (DDLPS), investigating the role of biomarkers CDK4 and MDM2.
- Results indicated that CDK4 was more highly expressed in DDLPS than in ALT/WDLPS, and the CDK4 inhibitor palbociclib showed promise in a sequential treatment approach when combined with lenvatinib, suggesting a new management strategy for DDLPS.
Osteosarcoma of the jaws (OSJ) is a relatively rare disease, accounting for between 2% and 10% of all cases of osteosarcoma. It is morphologically and radiologically identical to the trunk and extremity variant, but distinct in several crucial aspects. The lesion is characterized by sarcomatous cells which produce a variable amount of osteoid bone.
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