Evaluation of anti-acne property of purified bee venom serum in humans.

Objective: Acne vulgaris is a chronic dermatologic disease with four factors involved in the development of lesions. Treatments need to address as many of these underlying factors as possible in order to reduce acne lesions. As such, purified bee venom (PBV ) serum is an attractive therapeutic option for acne, but little data exist on the efficacy of this treatment strategy.

Effects of honeybee (Apis mellifera) venom on keratinocyte migration in vitro.

Background: Since the ancient times the skin aging application of honeybee venom (BV) is practiced and persisted until nowadays. The present study evaluated the effect of the honeybee venom (BV) on keratinocyte migration in wound healing model in vitro.

Objective: To access BV further as a cosmetic ingredient and a potential external application for topical uses, we performed studies to investigate the biologic effect of BV treatment on keratinocyte proliferation and migration in vitro.