Publications by authors named "Nicola Criscuolo"

Background: Bacterial antimicrobial resistance (AMR) is a global threat to both humans and livestock. Despite this, there is limited global consensus on data-informed, priority areas for intervention in both sectors. We compare current livestock AMR data collection efforts with other variables pertinent to human and livestock AMR to identify critical data gaps and mutual priorities.

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The rise of antimicrobial resistance (AMR) in animals is being fuelled by the widespread use of veterinary antimicrobials. China is the largest global consumer of veterinary antimicrobials, and improving AMR surveillance strategies in this region could help prioritize intervention and preserve antimicrobial efficacy. Here we mapped AMR rates in pigs, chickens and cattle in China using 446 surveys of event-based surveillance between 2000 and 2019 for foodborne bacteria, in combination with geospatial models to identify locations where conducting new surveys could have the highest benefits.

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Article Synopsis
  • Antimicrobial resistance (AMR) poses a significant health threat globally, particularly affecting humans and animals, necessitating urgent action, especially in low- and middle-income countries (LMICs) where meat demand is increasing.
  • Surveillance of AMR in LMICs is limited, creating a need for a centralized platform to inform policymakers and track resistance trends.
  • resistancebank.org is an online tool that gathers data from 1,285 surveys conducted on AMR in livestock, offering easy access to resistance rates and geographical reports, while encouraging further survey uploads to enhance its global database.
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Background: The inverse care law states that disadvantaged populations need more health care than advantaged populations but receive less. Gaps in COVID-19-related health care and infection control are not well understood. We aimed to examine inequalities in health in the care cascade from testing for SARS-CoV-2 to COVID-19-related hospitalisation, intensive care unit (ICU) admission, and death in Switzerland, a wealthy country strongly affected by the pandemic.

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Article Synopsis
  • Switzerland has seen a decrease in COVID-19 cases due to social distancing measures implemented on March 16, 2020, but easing restrictions risks a potential second wave of infections.
  • Hospitals need to prepare for a possible surge in ICU admissions from respiratory issues related to the virus.
  • The icumonitoring.ch platform provides detailed hospital-level projections for ICU usage by analyzing data on beds, ventilators, and COVID-19 case forecasts, and updates every few days to assist decision makers.
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Population genetics focuses on the analysis of genetic differences within and between-group of individuals and the inference of the populations' structure. These analyses are usually carried out using Bayesian clustering or maximum likelihood estimation algorithms that assign individuals to a given population depending on specific genetic patterns. Although several tools were developed to perform population genetics analysis, their standard graphical outputs may not be sufficiently informative for users lacking interactivity and complete information.

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Article Synopsis
  • The increasing global demand for animal protein has led to a significantly higher use of antimicrobials in animals compared to humans.
  • A study analyzing 901 surveys reveals that China and India are major resistance hotspots, with rising concerns also in Brazil and Kenya.
  • From 2000 to 2018, resistance to antimicrobials in chickens and pigs has notably increased, posing serious implications for both animal and human health.
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Morphometric, biochemical and genetic analyses were conducted on L. of Campania, an area of Southern Italy highly suited to the cultivation of olive trees and the production of extra virgin olive oil (EVOO). We aimed to characterize the distribution of morphological, biochemical and genetic diversity in this area and to develop a practical tool to aid traceability of oils.

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