Publications by authors named "Nicola Compagnone"

Purpose: Morphometric vertebral fractures (VFs) have been recently reported as an important component of the endocrine phenotype of COVID-19 and emerging data show negative respiratory sequelae at long-term follow-up in COVID-19 survivors. The aim of this study was to evaluate the impact of VFs on respiratory function in COVID-19 survivors.

Methods: We included patients referred to our Hospital Emergency Department and re-evaluated during follow-up.

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Article Synopsis
  • This study assessed the respiratory issues faced by COVID-19 survivors six months post-hospital discharge, finding that 37.3% had some form of respiratory dysfunction.
  • A logistic regression model was created to predict these issues based on factors like sex, obesity, and previous oxygen levels during admission.
  • The model showed 73% accuracy in identifying at-risk patients, outperforming simpler models that only considered initial oxygen levels.
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Background: Coronavirus disease 2019 acute respiratory distress syndrome (COVID-19 ARDS) is a disease that often requires invasive ventilation. Little is known about COVID-19 ARDS sequelae. We assessed the mid-term lung status of COVID-19 survivors and investigated factors associated with pulmonary sequelae.

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Background: Coronavirus disease 2019 (COVID-19) may leave behind an altered health status early after recovery. We evaluated the clinical status of COVID-19 survivors at three months after hospital discharge.

Methods: In this prospective observational cohort study, hospitalized patients aged ≥18 years, evaluated at one (M1) and three (M3) months post-discharge were enrolled.

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Purpose: To train and validate a predictive model of mortality for hospitalized COVID-19 patients based on lung densitometry.

Methods: Two-hundred-fifty-one patients with respiratory symptoms underwent CT few days after hospitalization. "Aerated" (AV), "consolidated" (CV) and "intermediate" (IV) lung sub-volumes were quantified by an operator-independent method based on individual HU maximum gradient recognition.

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Background: COVID-19 long-term sequelae are ill-defined since only a few studies have explored the long-term consequences of this disease so far.

Aims: To evaluate the 6-month respiratory outcome and exercise capacity of COVID-19 acute respiratory failure (ARF) patients treated with continuous positive airway pressure (CPAP) during the first wave of the ongoing COVID-19 pandemic.

Methods: A retrospective observational study included COVID-19 patients with ARF.

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