Publications by authors named "Nicola Bodley"
Article Synopsis
- - In South Africa, a study focused on women living with HIV (WLHIV) found a high prevalence of high-risk HPV infections, with 67.3% testing positive, particularly HPV16 and HPV18/45 types being common.
- - Many participants (91.3%) had never been screened for cervical cancer, and a significant portion (33.3%) showed abnormal cervical cytology results, strongly correlating this with HPV positivity.
- - The research emphasizes the importance of early HIV diagnosis and treatment, as well as regular cervical cancer screenings, particularly for those with low CD4 cell counts, to reduce cervical cancer risks among WLHIV.
Background: Data are required regarding the feasibility of conducting a randomized trial of point-of-care viral load (VL) testing to guide management of HIV viremia and to provide estimates of effect to guide potential future trial design.
Setting: Two public South African clinics during the dolutegravir-based antiretroviral therapy (ART) rollout.
Methods: We randomized adults receiving first-line ART, with recent VL ≥1000 copies/mL, in a 1:1 ratio to receive point-of-care Xpert HIV-1 VL versus standard-of-care laboratory VL testing after 12 weeks.