Characteristics of patients with familial versus sporadic prostate cancer.

Purpose: There are conflicting reports concerning whether prostate cancer in families with multiple affected members has different clinical and pathological features than sporadic cases. In our study we compared the clinical characteristics, pathological outcomes and the 7-year biochemical progression-free rate in patients with apparent sporadic prostate cancer, affected sibling pairs, families with multiple affected members and families meeting the Johns Hopkins criteria for hereditary prostate cancer.

Materials And Methods: From 1983 to 2003, 3,478 men underwent radical retropubic prostatectomy by a single surgeon (WJC).

Urology and the Nobel Prize.

The Nobel Prize in Physiology or Medicine, first awarded in 1901, was established by Alfred Nobel to acknowledge "those who during the preceding year had conferred the greatest benefit on mankind." Two urologists have achieved this daunting task: Werner Theodore Otto Forssmann (1956) and Charles Brenton Huggins (1966). This article reflects the lives and accomplishments of these men as an inspiration to those who have likewise dedicated themselves to the field of urology.