Complaints of Men with Uncorrected Distal Hypospadias.

Purpose: The few available reports regarding adults living with distal hypospadias give disparate views of the functional and aesthetic impact of this penile birth defect when it is not corrected. We reviewed symptoms and findings in consecutive men with unrepaired distal hypospadias and report those observations.

Material And Methods: Men with uncorrected hypospadias were queried regarding urinary symptoms, sexual dysfunction, and aesthetic concerns.

What Adults Teach Urologists About Hypospadias.

Knowledge regarding the impact of hypospadias in adults helps inform decision-making in childhood and potentially answers the question if repair should be delayed until during or after puberty. Earlier studies suggested that men with uncorrected hypospadias were either not aware of their condition or not bothered by it. Recent reports disagree and find that those with hypospadias are concerned by their difference and experience more penile dysfunction that men without this birth defect.

Do New Complications Develop during Puberty after Childhood Hypospadias Repair?

Purpose: We sought to determine if penile growth at puberty causes new complications after childhood hypospadias repair.

Materials And Methods: Consecutive Tanner 2-5 patients presenting with complications after childhood hypospadias repair were queried to determine if those problems occurred before, during or after puberty.

Results: There was a total of 82 patients, 15 Tanner 2-4, evaluated at a mean age of 28 years (range 12-66).

Parental Concerns of Boys with Hypospadias.

Introduction: Reports indicate many parents are negatively impacted by their child's birth defect, experiencing feelings of anxiety, shame, and blame. These reactions have been documented for several conditions, but not hypospadias. We surveyed parents of boys with hypospadias to determine their concerns.

Recurrent ventral curvature after proximal TIP hypospadias repair.

Extended Summary: Most boys with proximal hypospadias have ventral curvature (VC) which must be straightened while preserving the urethral plate to use TIP repair. That is usually done by dorsal plication (DP). However, we reported recurrent VC was commonly found after DP in boys with proximal urethroplasty complications, and have diagnosed VC in patients similarly straightened by WS.

Hyperbaric oxygen therapy for pediatric "hypospadias cripple"-evaluating the advantages regarding graft take.

Introduction: Hypospadias cripple patients pose a major surgical challenge with high complication rates attributed mainly to graft contraction. Hyperbaric oxygen therapy (HBOT) is an established treatment for compromised grafts and used extensively as a salvage therapy for compromised grafts and ischemic non-healing wounds.

Objective: We evaluated the graft-take rates in hypospadias cripple cases undergoing a staged tubularized autograft repair (STAG) and compared between patients treated with or without preemptive HBOT.

Insulin-Like Peptide 3 (INSL3) Serum Concentration During Human Male Fetal Life.

Insulin-like peptide 3 (INSL3), a protein hormone produced by Leydig cells, may play a crucial role in testicular descent as male INSL3 knockout mice have bilateral cryptorchidism. Previous studies have measured human fetal INSL3 levels in amniotic fluid only. To measure INSL3 serum levels and mRNA in fetal umbilical cord blood and fetal testes, respectively.

Hyperbaric Oxygen Therapy Improves Oral Graft Take in Hypospadias Staged Tubularized Autograft Reoperations.

Purpose: Increased complications following failed hypospadias repairs suggest that impaired wound healing is a contributing factor. We used perioperative hyperbaric oxygen therapy to promote wound healing determined by graft take in staged tubularized autograft reoperations using oral graft.

Materials And Methods: Hyperbaric oxygen therapy was recommended for patients with 3 or more failed hypospadias repairs, comprising 20 preoperative and 10 postoperative sessions.

Staged Tubularized Autograft Repair for Primary Proximal Hypospadias with 30-Degree or Greater Ventral Curvature.

Purpose: We report outcomes in consecutive patients with primary proximal hypospadias and ventral curvature 30 degrees or greater after degloving, all repaired with 2-stage tubularized autografts, a variation of the Nicolle-Bracka procedure.

Materials And Methods: Consecutive boys with proximal hypospadias and ventral curvature 30 degrees or greater after degloving underwent transection of the urethral plate. In addition, those with persistent ventral curvature 30 degrees or greater underwent 3 ventral corporotomies without corporal grafting for straightening.

Recurrence after management of meatal balanitis xerotica obliterans.

Introduction: We review outcomes after management of meatal balanitis xerotica obliterans (BXO). The primary outcome was recurrent meatal BXO.

Methods: A database comprising mostly hypospadias patients was queried for meatal BXO.

Primary hypospadias repair techniques: A review of the evidence.

This review summarizes data regarding commonly used surgical techniques to repair distal and proximal hypospadias. We review evidence concerning indications for various procedures used in primary hypospadias repair, and their complications, urinary function and esthetic results. Available evidence suggests TIP is preferable to Mathieu for distal hypospadias correction.