A web-based knowledge database to provide evidence-based information to cancer patients: Utilization within the PIKKO study.

Purpose: Cancer is associated with an urgent need for understandable and reliable information, which is often not satisfied by information available online. Therefore, as part of the PIKKO project, a web-based knowledge database (WDB) was introduced to provide cancer patients with quality-assured, evidence-based information. This paper aims to provide insights into the usage (Who? How? What?) and the effects regarding health literacy of the WDB.

Palladium-catalyzed enantioselective three-component synthesis of α-arylglycine derivatives from glyoxylic acid, sulfonamides and aryltrifluoroborates.

A palladium-catalyzed enantioselective three-component reaction of glyoxylic acid, sulfonamides and aryltrifluoroborates is described. This process provides modular access to the important α-arylglycine motif in moderate to good yields and enantioselectivies. The formed α-arylglycine products constitute useful building blocks for the synthesis of peptides or arylglycine-containing natural products.

The impact of the COVID-19 pandemic restrictions on the health care utilization of cancer patients.

Background: COVID-19 has impacted both society and medical care. While Germany entered the first lockdown in spring 2020, the PIKKO study (Patient information, communication and competence empowerment in oncology) was still active. The intervention modules, patient navigator (PN), services of the Saarland Cancer Society (SCS), psycho-social counseling and different courses, and online knowledge database (ODB) continued to be offered, but in an adapted form.

Patient information, communication and competence empowerment in oncology: Results and learnings from the PIKKO study.

Purpose: Many concepts for accompanying and supporting cancer patients exist and have been studied over time. One of them was PIKKO (a German acronym for "Patient information, communication and competence empowerment in oncology"), which combined a patient navigator, socio-legal and psychological counseling (with psychooncologists), courses dealing with various supportive aspects, and a knowledge database with validated and easy-to-understand disease-related information. The aim was to increase the patients' health-related quality of life (HRQoL), self-efficacy as well as health literacy and to reduce psychological complaints such as depression and anxiety.

[Psychometric Properties of the Qualiskope-A for Measuring Patient Satisfaction with Outpatient Medical Treatment: Use in Oncology and Transferability to Inpatient Care].

Aim: The Qualiskope-A is a German-language PREM (Patient Reported Experience Measure) which, with the help of 27 items allocated to four scales, enables measurement of patient satisfaction with outpatient medical treatment along four dimensions of patient satisfaction. This study examined whether the questionnaire delivers reliable results in an oncological population and whether its application can be extended to inpatient care.

Method: Required data was collected as part of the PIKKO study.

[Biographical Interviews with GDR Psychotherapists - First Hypotheses on their Social Positioning and Professional Action].

Objektive: First results of a socio-historical analysis of the life stories of GDR psychotherapists are presented. Interviews, carried out as part of the project , are intended to enable statements about social and family backgrounds, educational paths and social position. An exemplary case is presented in order to develop hypotheses for the design of professional behavior by GDR psychotherapists.

Healthcare Utilization and Costs in Sepsis Survivors in Germany-Secondary Analysis of a Prospective Cohort Study.

: Survivors of sepsis often face long-term sequelae after intensive care treatment. Compared to the period of hospitalization, little is known about the ambulatory healthcare utilization in sepsis patients. The study evaluated healthcare utilization and associated costs of sepsis care including allied health professions after initial hospitalization.

[Psychotherapeutic Literature of the GDR and FRG: A Comparative Citation Analysis].

Unlabelled: ZIEL: Erste Hypothesen zur wissenschaftlichen Rezeption von psychotherapeutischer Literatur aus der DDR und der Sowjetunion in einem Psychotherapieliteratur-Korpus der BRD (Praxis der Psychotherapie und Psychosomatik 1979-1990) sollten geprüft werden. Außerdem sollten inhaltliche Schwerpunkte der identifizierten wissenschaftlichen Communities verglichen werden.

Methodik: Es wurde eine bibliometrische und netzwerkanalytische Untersuchung von Zitationsbeziehungen sowie eine qualitative Inhaltsanalyse der Rezeption von DDR-Literatur und der thematischen Schwerpunkte der identifizierten wissenschaftlichen Communities in Literaturkorpora aus Ost und West durchgeführt.

Patient characteristics as predictors of sleep disturbances in multimorbid primary care patients - A secondary analysis.

Objective: The aim of the study was to identify patient characteristics (adult attachment, health status, number and severity of chronic conditions, social support) predictive sleep disturbances after 12 months.

Methods: In a secondary analysis of a prospective longitudinal study dealing with adult attachment and self-management, attachment- and health-related characteristics, socio-demographic data at baseline and symptoms of insomnia at the follow up (12 month later) was recorded by 219 patients between the ages of 50 and 85 years with multimorbidity in primary care. Adult attachment was measured by the ECR-RD12.

[The Influence of Attachment Characteristics and Disease-Specific Predictors on Health-Related Quality of Life in Elderly Patients with Multimorbidity].

Objective: Our aim was to further investigate factors influencing multimorbid primary care patients in relation to mental and physical quality of life.

Methods: 219 elderly patients over 50 years with multiple chronic conditions were assessed for quality of life, attachment, depression, and health status at baseline and follow-up after 12 months. Multivariate analyses were performed to identify potential predictors.

[Brief Scale to assess Social Support in Chronic Diseases (SUCE-4)].

Aim Of The Study: Social support is an important resource for coping with serious chronic diseases such as cancer. The available questionnaires for the measurement of social support are usually extensive. So far, available short versions do not completely aim at situation-specific requirements of the social environment of chronically ill patients.

Patient information, communication and competence empowerment in oncology (PIKKO) - evaluation of a supportive care intervention for overall oncological patients. Study protocol of a non-randomized controlled trial.

Background: Cancer patients have to undergo a difficult medical therapy and are also confronted with various psychological, social and economic problems. Support is available from many providers, but patients often gain no access to it. Accordingly, there is a need for a single point of contact that can provide advice, information and assistance.

Long-Term Courses of Sepsis Survivors: Effects of a Primary Care Management Intervention.

Background: Sepsis survivors face mental and physical sequelae even years after discharge from the intensive care unit. The aim of this study was to evaluate the long-term courses of sepsis survivors and the effects of a primary care management intervention in sepsis aftercare.

Methods: This study presents a 24-month follow-up of a randomized controlled trial that recruited 291 patients who survived sepsis (including septic shock) from nine German intensive care units.

Applicability of Motivational Interviewing for Chronic Disease Management in Primary Care Following a Web-Based E-Learning Course: Cross-Sectional Study.

Background: Motivational interviewing (MI) is an established communication method for enhancing intrinsic motivation for changing health behavior. E-learning can reduce the cost and time involved in providing continuing education and can be easily integrated into individual working arrangements and the daily routines of medical professionals. Thus, a Web-based course was devised to familiarize health professionals with different levels of education and expertise with MI techniques for patients with chronic conditions.

Panic Disorder in Primary Care.

Background: We evaluated a team-based program of exercises for patients with panic disorder with or without agoraphobia (PDA) in primary care.

Methods: 419 patients with PDA (mean age 46.2 years, standard deviation 14.

Evaluation of the short form of "Experience in Close Relationships" (Revised, German Version "ECR-RD12") - A tool to measure adult attachment in primary care.

Attachment theory helps us to understand patients´ health behavior. Attachment styles might explain patient differences in coping behavior, self-treatment, or patient-provider relationships. In primary care time constrains are relevant.

Patient-provider relationship as mediator between adult attachment and self-management in primary care patients with multiple chronic conditions.

Objective: The conceptual model of attachment theory has been applied to understand the predispositions of patients in medical care and the patient-provider relationship. In patients with chronic conditions insecure attachment was connected to poorer self-management. The patient-provider relationship is associated with a range of health related outcomes and self-management skills.

[Usual Care for Panic Disorder with/without Agoraphobia in Primary Care].

Objective: To describe therapy as usual (TAU) for panic disorder with/without agoraphobia (PDA) in primary care.

Method: Written survey of 38 general practitioners (GPs) who provided TAU to 189 patients with PDA as part of an interventional study. Data were analyzed descriptively.

Comprehensive Assessment of Composition and Thermochemical Variability by High Resolution GC/QToF-MS and the Advanced Distillation-Curve Method as a Basis of Comparison for Reference Fuel Development.

Commercial and military aviation is faced with challenges that include high fuel costs, undesirable emissions, and supply chain insecurity that result from the reliance on petroleum-based feedstocks. The development of alternative gas turbine fuels from renewable resources will likely be part of addressing these issues. The United States has established a target for one billion gallons of renewable fuels to enter the supply chain by 2018.

Effect of a Primary Care Management Intervention on Mental Health-Related Quality of Life Among Survivors of Sepsis: A Randomized Clinical Trial.

Importance: Survivors of sepsis face long-term sequelae that diminish health-related quality of life and result in increased care needs in the primary care setting, such as medication, physiotherapy, or mental health care.

Objective: To examine if a primary care-based intervention improves mental health-related quality of life.

Design, Setting, And Participants: Randomized clinical trial conducted between February 2011 and December 2014, enrolling 291 patients 18 years or older who survived sepsis (including septic shock), recruited from 9 intensive care units (ICUs) across Germany.

The Influence of Adult Attachment on Patient Self-Management in Primary Care--The Need for a Personalized Approach and Patient-Centred Care.

Objective: Self-management strategies are essential elements of evidence-based treatment in patients with chronic conditions in primary care. Our objective was to analyse different self-management skills and behaviours and their association to adult attachment in primary care patients with multiple chronic conditions.

Methods: In the apricare study (Adult Attachment in Primary Care) we used a prospective longitudinal design to examine the association between adult attachment and self-management in primary care patients with multimorbidity.

Density of biogas digestate depending on temperature and composition.

Density is one of the most important physical properties of biogas digestate to ensure an optimal dimensioning and a precise design of biogas plant components like stirring devices, pumps and heat exchangers. In this study the density of biogas digestates with different compositions was measured using pycnometers at ambient pressure in a temperature range from 293.15 to 313.

Correlation between viscosity, temperature and total solid content of algal biomass.

In this study equations have been set up allowing the calculation of the viscosity depending on temperature and total solid content of the algal sample and the shear rate. Therefore, the viscosity of the marine microalgae Nannochloropsis salina was determined experimentally at different temperatures and TS contents. Untreated, thermal pretreated and digested algal biomasses were investigated.